Overexpression and amplification of c-myc in the Syrian hamster kidney during estrogen carcinogenesis: a probable critical role in neoplastic transformation. [electronic resource]
Producer: 19990617Description: 2340-6 p. digitalISSN:- 0008-5472
- Aneuploidy
- Animals
- Carcinoma, Renal Cell -- chemically induced
- Cell Transformation, Neoplastic -- chemically induced
- Chromosome Mapping
- Cocarcinogenesis
- Cricetinae
- Diethylstilbestrol -- toxicity
- Estrogens
- Gene Amplification
- Gene Expression Regulation -- drug effects
- Gene Expression Regulation, Neoplastic -- drug effects
- Genes, fos
- Genes, myc
- In Situ Hybridization
- Karyotyping
- Kidney -- drug effects
- Kidney Cortex -- drug effects
- Kidney Medulla -- drug effects
- Kidney Neoplasms -- chemically induced
- Male
- Mesocricetus -- genetics
- Neoplasms, Hormone-Dependent -- chemically induced
- Orchiectomy
- Proliferating Cell Nuclear Antigen -- analysis
- RNA, Messenger -- biosynthesis
- RNA, Neoplasm -- biosynthesis
- Receptors, Estrogen -- drug effects
- S Phase
- Species Specificity
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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