Dermatopontin expression is decreased in hypertrophic scar and systemic sclerosis skin fibroblasts and is regulated by transforming growth factor-beta1, interleukin-4, and matrix collagen. [electronic resource]
Producer: 19990618Description: 706-10 p. digitalISSN:- 0022-202X
- Adolescent
- Adult
- Blotting, Northern
- Carrier Proteins -- biosynthesis
- Cell Adhesion Molecules -- biosynthesis
- Cells, Cultured
- Chondroitin Sulfate Proteoglycans
- Cicatrix, Hypertrophic -- metabolism
- Collagen -- physiology
- Dose-Response Relationship, Drug
- Down-Regulation -- physiology
- Extracellular Matrix Proteins
- Fibroblasts -- drug effects
- Humans
- Interleukin-4 -- pharmacology
- Middle Aged
- RNA, Messenger -- metabolism
- Scleroderma, Systemic -- metabolism
- Skin -- drug effects
- Time Factors
- Transforming Growth Factor beta -- pharmacology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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