Improving the efficacy of antibody-interleukin 2 fusion proteins by reducing their interaction with Fc receptors. [electronic resource]
Producer: 19990520Description: 2159-66 p. digitalISSN:- 0008-5472
- Animals
- Antibody-Dependent Cell Cytotoxicity
- Binding Sites
- Carcinoma -- pathology
- Complement System Proteins -- immunology
- Cytotoxicity, Immunologic
- Genes, Immunoglobulin
- Humans
- Immunoconjugates -- metabolism
- Immunoglobulin G -- genetics
- Immunoglobulin Heavy Chains -- genetics
- Immunoglobulin Isotypes -- metabolism
- Interleukin-2 -- genetics
- Kidney Neoplasms -- pathology
- Male
- Melanoma, Experimental -- pathology
- Metabolic Clearance Rate
- Mice
- Mice, Inbred BALB C
- Mice, SCID
- Mutagenesis, Site-Directed
- Prostatic Neoplasms -- pathology
- Receptors, Fc -- metabolism
- Recombinant Fusion Proteins -- metabolism
- Tissue Distribution
- Transfection
- Transplantation, Heterologous
- Tumor Cells, Cultured
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Publication Type: Journal Article
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