Down-regulation of human basophil IgE and FC epsilon RI alpha surface densities and mediator release by anti-IgE-infusions is reversible in vitro and in vivo. [electronic resource]
Producer: 19990520Description: 5624-30 p. digitalISSN:- 0022-1767
- Adult
- Antibodies, Anti-Idiotypic -- administration & dosage
- Basophils -- immunology
- Cells, Cultured
- Down-Regulation -- immunology
- Female
- Follow-Up Studies
- Histamine -- blood
- Histamine Release
- Humans
- Immunoglobulin E -- biosynthesis
- Immunoglobulin G -- physiology
- Infusions, Intravenous
- Leukocyte Count
- Male
- Receptors, Antigen, B-Cell -- biosynthesis
- Receptors, IgE -- biosynthesis
- Respiratory Hypersensitivity -- therapy
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Publication Type: Clinical Trial; Clinical Trial, Phase I; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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