Modulation of wild-type p53 activity by mutant p53 R273H depends on the p53 responsive element (p53RE). A comparative study between the p53REs of the MDM2, WAFI/Cip1 and Bax genes in the lung cancer environment. WAFI/Cip1 = WAF1/Cip1. [electronic resource]
Producer: 19990520Description: 579-87 p. digitalISSN:- 0250-7005
- Cyclin-Dependent Kinase Inhibitor p21
- Cyclins -- genetics
- DNA -- metabolism
- Humans
- Lung Neoplasms -- genetics
- Mutation
- Nuclear Proteins
- Promoter Regions, Genetic
- Proto-Oncogene Proteins -- genetics
- Proto-Oncogene Proteins c-bcl-2
- Proto-Oncogene Proteins c-mdm2
- Response Elements
- Transcription, Genetic
- Transfection
- Tumor Suppressor Protein p53 -- physiology
- bcl-2-Associated X Protein
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Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
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