The effects of rifampin and rifabutin on the pharmacokinetics and pharmacodynamics of a combination oral contraceptive. [electronic resource]
Producer: 19990506Description: 428-38 p. digitalISSN:- 0009-9236
- Adult
- Antibiotics, Antitubercular -- pharmacology
- Contraceptives, Oral, Hormonal -- pharmacokinetics
- Cross-Over Studies
- Cytochrome P-450 CYP3A
- Cytochrome P-450 Enzyme System -- metabolism
- Double-Blind Method
- Enzyme Inhibitors -- pharmacology
- Ethinyl Estradiol -- pharmacokinetics
- Female
- Follicle Stimulating Hormone -- blood
- Humans
- Luteinizing Hormone -- blood
- Mixed Function Oxygenases -- metabolism
- Norethindrone -- pharmacokinetics
- Prospective Studies
- Rifabutin -- pharmacology
- Rifampin -- pharmacology
- gamma-Glutamyltransferase -- blood
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Publication Type: Clinical Trial; Journal Article; Randomized Controlled Trial; Research Support, U.S. Gov't, P.H.S.
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