Phase I/II trial of (131)I-MN-14F(ab)2 anti-carcinoembryonic antigen monoclonal antibody in the treatment of patients with metastatic medullary thyroid carcinoma. [electronic resource]
Producer: 19990513Description: 1828-42 p. digitalISSN:- 0008-543X
- Adult
- Aged
- Aged, 80 and over
- Animals
- Antibodies, Anti-Idiotypic -- biosynthesis
- Antibodies, Monoclonal -- pharmacokinetics
- Antibodies, Monoclonal, Humanized
- Antigens, Neoplasm -- immunology
- Antineoplastic Combined Chemotherapy Protocols -- therapeutic use
- Calcitonin -- blood
- Carcinoembryonic Antigen -- immunology
- Carcinoma, Medullary -- drug therapy
- Combined Modality Therapy
- Female
- Humans
- Immunoconjugates -- pharmacokinetics
- Iodine Radioisotopes -- administration & dosage
- Male
- Metabolic Clearance Rate
- Mice
- Middle Aged
- Neck Dissection
- Neoplasm Proteins -- blood
- Radioimmunotherapy
- Radiotherapy Dosage
- Thyroid Neoplasms -- drug therapy
- Thyroidectomy
- Tissue Distribution
- Treatment Outcome
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Publication Type: Clinical Trial; Clinical Trial, Phase I; Clinical Trial, Phase II; Journal Article; Research Support, U.S. Gov't, P.H.S.
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