Retrovirus-mediated gene transfer of the human multidrug resistance-associated protein into hematopoietic cells protects mice from chemotherapy-induced leukopenia. [electronic resource]
Producer: 19990616Description: 801-11 p. digitalISSN:- 1043-0342
- ATP-Binding Cassette Transporters -- genetics
- Animals
- Antineoplastic Agents -- adverse effects
- Blotting, Southern
- Bone Marrow Cells -- metabolism
- Dose-Response Relationship, Drug
- Doxorubicin -- adverse effects
- Flow Cytometry
- Gene Transfer Techniques
- Hematopoietic Stem Cells -- metabolism
- Humans
- Leukocytes -- drug effects
- Leukopenia -- chemically induced
- Male
- Mice
- Mice, Inbred C57BL
- Multidrug Resistance-Associated Proteins
- Retroviridae -- genetics
- Reverse Transcriptase Polymerase Chain Reaction
- Time Factors
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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