CLN3 defines a novel antiapoptotic pathway operative in neurodegeneration and mediated by ceramide. [electronic resource]
Producer: 19990622Description: 294-308 p. digitalISSN:- 1096-7192
- Apoptosis
- Blotting, Western
- Cell Division
- Cell Line
- Cell Survival
- Cells, Cultured
- Ceramides -- metabolism
- Cyclins
- Dose-Response Relationship, Drug
- Etoposide -- pharmacology
- Humans
- Membrane Glycoproteins -- metabolism
- Models, Biological
- Molecular Chaperones -- metabolism
- Neurodegenerative Diseases -- metabolism
- Poly(ADP-ribose) Polymerases -- metabolism
- Reverse Transcriptase Polymerase Chain Reaction
- Saccharomyces cerevisiae Proteins
- Sphingosine -- analogs & derivatives
- Staurosporine -- pharmacology
- Time Factors
- Transfection
- Vincristine -- pharmacology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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