Colitis-inducing potency of CD4+ T cells in immunodeficient, adoptive hosts depends on their state of activation, IL-12 responsiveness, and CD45RB surface phenotype. [electronic resource]
Producer: 19990413Description: 3702-10 p. digitalISSN:- 0022-1767
- Adoptive Transfer
- Animals
- CD4-Positive T-Lymphocytes -- immunology
- DNA-Binding Proteins -- genetics
- Female
- Immunophenotyping
- Inflammatory Bowel Diseases -- etiology
- Interferon-gamma -- biosynthesis
- Interleukin-12 -- pharmacology
- Interphase -- immunology
- Leukocyte Common Antigens -- biosynthesis
- Lymphocyte Activation
- Mice
- Mice, Inbred BALB C
- Mice, Knockout
- Mice, SCID
- STAT4 Transcription Factor
- Severe Combined Immunodeficiency -- immunology
- Signal Transduction -- genetics
- Th1 Cells -- pathology
- Trans-Activators -- genetics
- Tumor Necrosis Factor-alpha -- biosynthesis
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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