The transcriptional regulator Rel is essential for antigen receptor-mediated stimulation of mature T cells but dispensable for positive and negative selection of thymocytes and T cell apoptosis. [electronic resource]
Producer: 19990421Description: 928-35 p. digitalISSN:- 0014-2980
- Animals
- Apoptosis -- immunology
- CD3 Complex -- immunology
- CD8-Positive T-Lymphocytes -- immunology
- Cell Differentiation
- Cell Nucleus -- metabolism
- Clonal Anergy
- Female
- Isoantibodies -- immunology
- Male
- Mice
- Mice, Inbred C57BL
- Mice, Knockout
- Mice, Transgenic
- Proto-Oncogene Proteins -- genetics
- Proto-Oncogene Proteins c-rel
- Receptors, Antigen, T-Cell, alpha-beta -- genetics
- T-Lymphocytes -- cytology
- Thymus Gland -- cytology
- Transcription Factors -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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