A specific inhibitor of the p38 mitogen activated protein kinase affects differentially the production of various cytokines by activated human T cells: dependence on CD28 signaling and preferential inhibition of IL-10 production. [electronic resource]
Producer: 19990429Description: 87-95 p. digitalISSN:- 0008-8749
- CD28 Antigens -- physiology
- Calcium-Calmodulin-Dependent Protein Kinases -- antagonists & inhibitors
- Cells, Cultured
- Cytokines -- biosynthesis
- Dose-Response Relationship, Drug
- Humans
- Imidazoles -- pharmacology
- Interferon-gamma -- biosynthesis
- Interleukin-10 -- biosynthesis
- Interleukin-2 -- biosynthesis
- Lymphocyte Activation -- drug effects
- Mitogen-Activated Protein Kinases
- Pyridines -- pharmacology
- RNA, Messenger -- analysis
- T-Lymphocytes -- metabolism
- p38 Mitogen-Activated Protein Kinases
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Publication Type: Journal Article
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