Activation of the human RANTES gene promoter in a macrophage cell line by lipopolysaccharide is dependent on stress-activated protein kinases and the IkappaB kinase cascade: implications for exacerbation of allergic inflammation by environmental pollutants. [electronic resource]
Producer: 19990413Description: 287-301 p. digitalISSN:- 1521-6616
- Air Pollutants -- immunology
- Calcium-Calmodulin-Dependent Protein Kinases -- metabolism
- Chemokine CCL5 -- genetics
- Genes, Reporter
- Humans
- Hydroquinones -- immunology
- Hypersensitivity -- immunology
- I-kappa B Kinase
- JNK Mitogen-Activated Protein Kinases
- Lipopolysaccharides -- immunology
- Macrophages -- immunology
- Mitogen-Activated Protein Kinases
- NF-kappa B -- metabolism
- Oxidation-Reduction
- Promoter Regions, Genetic
- Protein Binding
- Protein Serine-Threonine Kinases -- metabolism
- RNA, Messenger -- analysis
- Response Elements
- Signal Transduction
- Transcription Factor AP-1 -- metabolism
- Transcriptional Activation
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Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
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