Acylation of naturally occurring and synthetic 1-deoxysphinganines by ceramide synthase. Formation of N-palmitoyl-aminopentol produces a toxic metabolite of hydrolyzed fumonisin, AP1, and a new category of ceramide synthase inhibitor. (Record no. 9634060)

MARC details
000 -LEADER
fixed length control field 01598 a2200421 4500
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20250513145608.0
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 199808s 0 0 eng d
022 ## - INTERNATIONAL STANDARD SERIAL NUMBER
International Standard Serial Number 0021-9258
024 7# - OTHER STANDARD IDENTIFIER
Standard number or code 10.1074/jbc.273.30.19060
Source of number or code doi
040 ## - CATALOGING SOURCE
Original cataloging agency NLM
Language of cataloging eng
Transcribing agency NLM
100 1# - MAIN ENTRY--PERSONAL NAME
Personal name Humpf, H U
264 #0 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE
Date of production, publication, distribution, manufacture, or copyright notice 19980820
245 00 - TITLE STATEMENT
Title Acylation of naturally occurring and synthetic 1-deoxysphinganines by ceramide synthase. Formation of N-palmitoyl-aminopentol produces a toxic metabolite of hydrolyzed fumonisin, AP1, and a new category of ceramide synthase inhibitor.
Medium [electronic resource]
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Name of publisher, distributor, etc. The Journal of biological chemistry
Date of publication, distribution, etc. Jul 1998
300 ## - PHYSICAL DESCRIPTION
Extent 19060-4 p.
Other physical details digital
500 ## - GENERAL NOTE
General note Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Acylation
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Carboxylic Acids
General subdivision chemistry
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Fumonisins
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Humans
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Hydrolysis
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Kinetics
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Mycotoxins
General subdivision chemistry
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Oxidoreductases
General subdivision antagonists & inhibitors
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Palmitic Acid
General subdivision metabolism
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Pancreatitis-Associated Proteins
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Sphingosine
General subdivision analogs & derivatives
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Schmelz, E M
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Meredith, F I
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Vesper, H
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Vales, T R
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Wang, E
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Menaldino, D S
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Liotta, D C
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Merrill, A H
773 0# - HOST ITEM ENTRY
Title The Journal of biological chemistry
Related parts vol. 273
-- no. 30
-- p. 19060-4
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://doi.org/10.1074/jbc.273.30.19060">https://doi.org/10.1074/jbc.273.30.19060</a>
Public note Available from publisher's website

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