Directed evolution of adenine base editors with increased activity and therapeutic application. (Record no. 30851732)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 01607 a2200505 4500 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250518095143.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 202010s 0 0 eng d |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER | |
| International Standard Serial Number | 1546-1696 |
| 024 7# - OTHER STANDARD IDENTIFIER | |
| Standard number or code | 10.1038/s41587-020-0491-6 |
| Source of number or code | doi |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | NLM |
| Language of cataloging | eng |
| Transcribing agency | NLM |
| 100 1# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Gaudelli, Nicole M |
| 264 #0 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Date of production, publication, distribution, manufacture, or copyright notice | 20201007 |
| 245 00 - TITLE STATEMENT | |
| Title | Directed evolution of adenine base editors with increased activity and therapeutic application. |
| Medium | [electronic resource] |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Name of publisher, distributor, etc. | Nature biotechnology |
| Date of publication, distribution, etc. | 07 2020 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 892-900 p. |
| Other physical details | digital |
| 500 ## - GENERAL NOTE | |
| General note | Publication Type: Journal Article |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Adenine |
| General subdivision | metabolism |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Adenosine Deaminase |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | CRISPR-Cas Systems |
| General subdivision | genetics |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Cytosine |
| General subdivision | metabolism |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | DNA |
| General subdivision | genetics |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Gene Editing |
| General subdivision | methods |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | HEK293 Cells |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Humans |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Mutation |
| General subdivision | genetics |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | RNA, Guide, CRISPR-Cas Systems |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Lam, Dieter K |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Rees, Holly A |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Solá-Esteves, Noris M |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Barrera, Luis A |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Born, David A |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Edwards, Aaron |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Gehrke, Jason M |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Lee, Seung-Joo |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Liquori, Alexander J |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Murray, Ryan |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Packer, Michael S |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Rinaldi, Conrad |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Slaymaker, Ian M |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Yen, Jonathan |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Young, Lauren E |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ciaramella, Giuseppe |
| 773 0# - HOST ITEM ENTRY | |
| Title | Nature biotechnology |
| Related parts | vol. 38 |
| -- | no. 7 |
| -- | p. 892-900 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://doi.org/10.1038/s41587-020-0491-6">https://doi.org/10.1038/s41587-020-0491-6</a> |
| Public note | Available from publisher's website |
No items available.