CRISPR/Cas9-generated models uncover therapeutic vulnerabilities of del(11q) CLL cells to dual BCR and PARP inhibition. (Record no. 30553905)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02463 a2200673 4500 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250518082208.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 202010s 0 0 eng d |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER | |
| International Standard Serial Number | 1476-5551 |
| 024 7# - OTHER STANDARD IDENTIFIER | |
| Standard number or code | 10.1038/s41375-020-0714-3 |
| Source of number or code | doi |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | NLM |
| Language of cataloging | eng |
| Transcribing agency | NLM |
| 100 1# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Quijada-Álamo, Miguel |
| 264 #0 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Date of production, publication, distribution, manufacture, or copyright notice | 20201007 |
| 245 00 - TITLE STATEMENT | |
| Title | CRISPR/Cas9-generated models uncover therapeutic vulnerabilities of del(11q) CLL cells to dual BCR and PARP inhibition. |
| Medium | [electronic resource] |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Name of publisher, distributor, etc. | Leukemia |
| Date of publication, distribution, etc. | 06 2020 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 1599-1612 p. |
| Other physical details | digital |
| 500 ## - GENERAL NOTE | |
| General note | Publication Type: Journal Article; Research Support, Non-U.S. Gov't |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Adenine |
| General subdivision | analogs & derivatives |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Animals |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Antineoplastic Combined Chemotherapy Protocols |
| General subdivision | pharmacology |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Ataxia Telangiectasia Mutated Proteins |
| General subdivision | genetics |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | CRISPR-Cas Systems |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Cell Line, Tumor |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Chromosome Deletion |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Chromosomes, Human, Pair 11 |
| General subdivision | genetics |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Drug Synergism |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Humans |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Leukemia, Lymphocytic, Chronic, B-Cell |
| General subdivision | genetics |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Mice |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Mutagenesis, Site-Directed |
| General subdivision | methods |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Mutation |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Phthalazines |
| General subdivision | pharmacology |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Piperazines |
| General subdivision | pharmacology |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Piperidines |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Poly (ADP-Ribose) Polymerase-1 |
| General subdivision | antagonists & inhibitors |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Poly(ADP-ribose) Polymerase Inhibitors |
| General subdivision | pharmacology |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Proto-Oncogene Proteins c-bcr |
| General subdivision | antagonists & inhibitors |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Pyrazoles |
| General subdivision | pharmacology |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Pyrimidines |
| General subdivision | pharmacology |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Xenograft Model Antitumor Assays |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Hernández-Sánchez, María |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Alonso-Pérez, Verónica |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Rodríguez-Vicente, Ana E |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | García-Tuñón, Ignacio |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Martín-Izquierdo, Marta |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Hernández-Sánchez, Jesús María |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Herrero, Ana B |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Bastida, José María |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | San Segundo, Laura |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Gruber, Michaela |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | García, Juan Luis |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Yin, Shanye |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ten Hacken, Elisa |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Benito, Rocío |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ordóñez, José Luis |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Wu, Catherine J |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Hernández-Rivas, Jesús María |
| 773 0# - HOST ITEM ENTRY | |
| Title | Leukemia |
| Related parts | vol. 34 |
| -- | no. 6 |
| -- | p. 1599-1612 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://doi.org/10.1038/s41375-020-0714-3">https://doi.org/10.1038/s41375-020-0714-3</a> |
| Public note | Available from publisher's website |
No items available.