Pharmacologic Characterization of JNJ-42226314, [1-(4-Fluorophenyl)indol-5-yl]-[3-[4-(thiazole-2-carbonyl)piperazin-1-yl]azetidin-1-yl]methanone, a Reversible, Selective, and Potent Monoacylglycerol Lipase Inhibitor. (Record no. 30402804)
[ view plain ]
| 000 -LEADER | |
|---|---|
| fixed length control field | 02599 a2200769 4500 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250518073615.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 202007s 0 0 eng d |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER | |
| International Standard Serial Number | 1521-0103 |
| 024 7# - OTHER STANDARD IDENTIFIER | |
| Standard number or code | 10.1124/jpet.119.262139 |
| Source of number or code | doi |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | NLM |
| Language of cataloging | eng |
| Transcribing agency | NLM |
| 100 1# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Wyatt, Ryan M |
| 264 #0 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Date of production, publication, distribution, manufacture, or copyright notice | 20200706 |
| 245 00 - TITLE STATEMENT | |
| Title | Pharmacologic Characterization of JNJ-42226314, [1-(4-Fluorophenyl)indol-5-yl]-[3-[4-(thiazole-2-carbonyl)piperazin-1-yl]azetidin-1-yl]methanone, a Reversible, Selective, and Potent Monoacylglycerol Lipase Inhibitor. |
| Medium | [electronic resource] |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Name of publisher, distributor, etc. | The Journal of pharmacology and experimental therapeutics |
| Date of publication, distribution, etc. | 03 2020 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 339-353 p. |
| Other physical details | digital |
| 500 ## - GENERAL NOTE | |
| General note | Publication Type: Journal Article |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Animals |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Binding, Competitive |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Brain |
| General subdivision | drug effects |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Dose-Response Relationship, Drug |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Enzyme Inhibitors |
| General subdivision | blood |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Escherichia coli |
| General subdivision | enzymology |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | HeLa Cells |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Humans |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Kinetics |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Leukocytes, Mononuclear |
| General subdivision | drug effects |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Male |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Mice, Inbred C57BL |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Molecular Structure |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Monoacylglycerol Lipases |
| General subdivision | antagonists & inhibitors |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Pain |
| General subdivision | drug therapy |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Piperazines |
| General subdivision | blood |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Protein Binding |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Rats, Sprague-Dawley |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Receptor, Cannabinoid, CB1 |
| General subdivision | agonists |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Receptor, Cannabinoid, CB2 |
| General subdivision | agonists |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Sleep, REM |
| General subdivision | drug effects |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Substrate Specificity |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Fraser, Ian |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Welty, Natalie |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Lord, Brian |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Wennerholm, Michelle |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Sutton, Steven |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ameriks, Michael K |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Dugovic, Christine |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Yun, Sujin |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | White, Allison |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Nguyen, Leslie |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Koudriakova, Tatiana |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Tian, Gaochao |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Suarez, Javier |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Szewczuk, Lawrence |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Bonnette, William |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ahn, Kay |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ghosh, Brahma |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Flores, Christopher M |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Connolly, Peter J |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Zhu, Bin |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Macielag, Mark J |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Brandt, Michael R |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Chevalier, Kristen |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Zhang, Sui-Po |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Lovenberg, Timothy |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Bonaventure, Pascal |
| 773 0# - HOST ITEM ENTRY | |
| Title | The Journal of pharmacology and experimental therapeutics |
| Related parts | vol. 372 |
| -- | no. 3 |
| -- | p. 339-353 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://doi.org/10.1124/jpet.119.262139">https://doi.org/10.1124/jpet.119.262139</a> |
| Public note | Available from publisher's website |
No items available.