A Highly Bioactive Lys-Deficient IFN Leads to a Site-Specific Di-PEGylated IFN with Equivalent Bioactivity to That of Unmodified IFN-α2b. (Record no. 28896524)
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000 -LEADER | |
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fixed length control field | 01647 a2200481 4500 |
005 - DATE AND TIME OF LATEST TRANSACTION | |
control field | 20250518001644.0 |
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
fixed length control field | 201910s 0 0 eng d |
022 ## - INTERNATIONAL STANDARD SERIAL NUMBER | |
International Standard Serial Number | 2161-5063 |
024 7# - OTHER STANDARD IDENTIFIER | |
Standard number or code | 10.1021/acssynbio.8b00188 |
Source of number or code | doi |
040 ## - CATALOGING SOURCE | |
Original cataloging agency | NLM |
Language of cataloging | eng |
Transcribing agency | NLM |
100 1# - MAIN ENTRY--PERSONAL NAME | |
Personal name | Imada, Takashi |
264 #0 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
Date of production, publication, distribution, manufacture, or copyright notice | 20191003 |
245 00 - TITLE STATEMENT | |
Title | A Highly Bioactive Lys-Deficient IFN Leads to a Site-Specific Di-PEGylated IFN with Equivalent Bioactivity to That of Unmodified IFN-α2b. |
Medium | [electronic resource] |
260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
Name of publisher, distributor, etc. | ACS synthetic biology |
Date of publication, distribution, etc. | 11 2018 |
300 ## - PHYSICAL DESCRIPTION | |
Extent | 2537-2546 p. |
Other physical details | digital |
500 ## - GENERAL NOTE | |
General note | Publication Type: Journal Article; Research Support, Non-U.S. Gov't |
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
Topical term or geographic name entry element | Animals |
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
Topical term or geographic name entry element | Antiviral Agents |
General subdivision | blood |
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
Topical term or geographic name entry element | Directed Molecular Evolution |
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
Topical term or geographic name entry element | Humans |
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
Topical term or geographic name entry element | Interferon alpha-2 |
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
Topical term or geographic name entry element | Interferon-alpha |
General subdivision | chemistry |
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
Topical term or geographic name entry element | Lysine |
General subdivision | deficiency |
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
Topical term or geographic name entry element | Mice |
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
Topical term or geographic name entry element | Mutagenesis, Site-Directed |
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
Topical term or geographic name entry element | Polyethylene Glycols |
General subdivision | chemistry |
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
Topical term or geographic name entry element | Protein Stability |
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
Topical term or geographic name entry element | Recombinant Proteins |
General subdivision | biosynthesis |
700 1# - ADDED ENTRY--PERSONAL NAME | |
Personal name | Moriya, Koji |
700 1# - ADDED ENTRY--PERSONAL NAME | |
Personal name | Uchiyama, Masahiko |
700 1# - ADDED ENTRY--PERSONAL NAME | |
Personal name | Inukai, Naoto |
700 1# - ADDED ENTRY--PERSONAL NAME | |
Personal name | Hitotsuyanagi, Mitsuhiro |
700 1# - ADDED ENTRY--PERSONAL NAME | |
Personal name | Masuda, Akiko |
700 1# - ADDED ENTRY--PERSONAL NAME | |
Personal name | Suzuki, Takehiro |
700 1# - ADDED ENTRY--PERSONAL NAME | |
Personal name | Ayukawa, Shotaro |
700 1# - ADDED ENTRY--PERSONAL NAME | |
Personal name | Tagawa, Yo-Ichi |
700 1# - ADDED ENTRY--PERSONAL NAME | |
Personal name | Dohmae, Naoshi |
700 1# - ADDED ENTRY--PERSONAL NAME | |
Personal name | Kohara, Michinori |
700 1# - ADDED ENTRY--PERSONAL NAME | |
Personal name | Yamamura, Masayuki |
700 1# - ADDED ENTRY--PERSONAL NAME | |
Personal name | Kiga, Daisuke |
773 0# - HOST ITEM ENTRY | |
Title | ACS synthetic biology |
Related parts | vol. 7 |
-- | no. 11 |
-- | p. 2537-2546 |
856 40 - ELECTRONIC LOCATION AND ACCESS | |
Uniform Resource Identifier | <a href="https://doi.org/10.1021/acssynbio.8b00188">https://doi.org/10.1021/acssynbio.8b00188</a> |
Public note | Available from publisher's website |
No items available.