Loss of USP28-mediated BRAF degradation drives resistance to RAF cancer therapies. (Record no. 28508670)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02195 a2200661 4500 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250517222221.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 201906s 0 0 eng d |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER | |
| International Standard Serial Number | 1540-9538 |
| 024 7# - OTHER STANDARD IDENTIFIER | |
| Standard number or code | 10.1084/jem.20171960 |
| Source of number or code | doi |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | NLM |
| Language of cataloging | eng |
| Transcribing agency | NLM |
| 100 1# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Saei, Azad |
| 264 #0 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Date of production, publication, distribution, manufacture, or copyright notice | 20190624 |
| 245 00 - TITLE STATEMENT | |
| Title | Loss of USP28-mediated BRAF degradation drives resistance to RAF cancer therapies. |
| Medium | [electronic resource] |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Name of publisher, distributor, etc. | The Journal of experimental medicine |
| Date of publication, distribution, etc. | 07 2018 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 1913-1928 p. |
| Other physical details | digital |
| 500 ## - GENERAL NOTE | |
| General note | Publication Type: Journal Article; Research Support, Non-U.S. Gov't |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Animals |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Apoptosis |
| General subdivision | drug effects |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Cell Line, Tumor |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Down-Regulation |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Drug Resistance, Neoplasm |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | F-Box-WD Repeat-Containing Protein 7 |
| General subdivision | metabolism |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Gene Deletion |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Glycine |
| General subdivision | analogs & derivatives |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | HEK293 Cells |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Humans |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | MAP Kinase Signaling System |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Melanoma |
| General subdivision | drug therapy |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Mice |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Prognosis |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Protein Stability |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Proteolysis |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Proto-Oncogene Proteins B-raf |
| General subdivision | metabolism |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Sulfones |
| General subdivision | pharmacology |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Ubiquitin Thiolesterase |
| General subdivision | deficiency |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Vemurafenib |
| General subdivision | pharmacology |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Palafox, Marta |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Benoukraf, Touati |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Kumari, Nishi |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Jaynes, Patrick William |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Iyengar, Prasanna Vasudevan |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Muñoz-Couselo, Eva |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Nuciforo, Paolo |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Cortés, Javier |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Nötzel, Christopher |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Kumarakulasinghe, Nesaretnam Barr |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Richard, John Lalith Charles |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Bin Adam Isa, Zul Fazreen |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Pang, Brendan |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Guzman, Marta |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Siqin, Zhou |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Yang, Henry |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Tam, Wai Leong |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Serra, Violeta |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Eichhorn, Pieter Johan Adam |
| 773 0# - HOST ITEM ENTRY | |
| Title | The Journal of experimental medicine |
| Related parts | vol. 215 |
| -- | no. 7 |
| -- | p. 1913-1928 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://doi.org/10.1084/jem.20171960">https://doi.org/10.1084/jem.20171960</a> |
| Public note | Available from publisher's website |
No items available.