SHP2 inhibition restores sensitivity in ALK-rearranged non-small-cell lung cancer resistant to ALK inhibitors. (Record no. 28145761)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02575 a2200781 4500 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250517203609.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 201905s 0 0 eng d |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER | |
| International Standard Serial Number | 1546-170X |
| 024 7# - OTHER STANDARD IDENTIFIER | |
| Standard number or code | 10.1038/nm.4497 |
| Source of number or code | doi |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | NLM |
| Language of cataloging | eng |
| Transcribing agency | NLM |
| 100 1# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Dardaei, Leila |
| 264 #0 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Date of production, publication, distribution, manufacture, or copyright notice | 20190520 |
| 245 00 - TITLE STATEMENT | |
| Title | SHP2 inhibition restores sensitivity in ALK-rearranged non-small-cell lung cancer resistant to ALK inhibitors. |
| Medium | [electronic resource] |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Name of publisher, distributor, etc. | Nature medicine |
| Date of publication, distribution, etc. | 05 2018 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 512-517 p. |
| Other physical details | digital |
| 500 ## - GENERAL NOTE | |
| General note | Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Anaplastic Lymphoma Kinase |
| General subdivision | antagonists & inhibitors |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Animals |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Carcinoma, Non-Small-Cell Lung |
| General subdivision | enzymology |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Cell Line, Tumor |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Drug Resistance, Neoplasm |
| General subdivision | drug effects |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Extracellular Signal-Regulated MAP Kinases |
| General subdivision | metabolism |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Female |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Gene Rearrangement |
| General subdivision | genetics |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Humans |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Lung Neoplasms |
| General subdivision | enzymology |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Mice, Nude |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Protein Kinase Inhibitors |
| General subdivision | pharmacology |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Protein Tyrosine Phosphatase, Non-Receptor Type 11 |
| General subdivision | antagonists & inhibitors |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Pyrimidines |
| General subdivision | pharmacology |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | RNA, Small Interfering |
| General subdivision | metabolism |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Sulfones |
| General subdivision | pharmacology |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Wang, Hui Qin |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Singh, Manrose |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Fordjour, Paul |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Shaw, Katherine X |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Yoda, Satoshi |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Kerr, Grainne |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Yu, Kristine |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Liang, Jinsheng |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Cao, Yichen |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Chen, Yan |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Lawrence, Michael S |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Langenbucher, Adam |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Gainor, Justin F |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Friboulet, Luc |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Dagogo-Jack, Ibiayi |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Myers, David T |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Labrot, Emma |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ruddy, David |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Parks, Melissa |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Lee, Dana |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | DiCecca, Richard H |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Moody, Susan |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Hao, Huaixiang |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mohseni, Morvarid |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | LaMarche, Matthew |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Williams, Juliet |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Hoffmaster, Keith |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Caponigro, Giordano |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Shaw, Alice T |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Hata, Aaron N |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Benes, Cyril H |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Li, Fang |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Engelman, Jeffrey A |
| 773 0# - HOST ITEM ENTRY | |
| Title | Nature medicine |
| Related parts | vol. 24 |
| -- | no. 4 |
| -- | p. 512-517 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://doi.org/10.1038/nm.4497">https://doi.org/10.1038/nm.4497</a> |
| Public note | Available from publisher's website |
No items available.