Discovery of LY3104607: A Potent and Selective G Protein-Coupled Receptor 40 (GPR40) Agonist with Optimized Pharmacokinetic Properties to Support Once Daily Oral Treatment in Patients with Type 2 Diabetes Mellitus. (Record no. 27884964)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02176 a2200637 4500 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250517191502.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 201902s 0 0 eng d |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER | |
| International Standard Serial Number | 1520-4804 |
| 024 7# - OTHER STANDARD IDENTIFIER | |
| Standard number or code | 10.1021/acs.jmedchem.7b01411 |
| Source of number or code | doi |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | NLM |
| Language of cataloging | eng |
| Transcribing agency | NLM |
| 100 1# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Hamdouchi, Chafiq |
| 264 #0 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Date of production, publication, distribution, manufacture, or copyright notice | 20190218 |
| 245 00 - TITLE STATEMENT | |
| Title | Discovery of LY3104607: A Potent and Selective G Protein-Coupled Receptor 40 (GPR40) Agonist with Optimized Pharmacokinetic Properties to Support Once Daily Oral Treatment in Patients with Type 2 Diabetes Mellitus. |
| Medium | [electronic resource] |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Name of publisher, distributor, etc. | Journal of medicinal chemistry |
| Date of publication, distribution, etc. | 02 2018 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 934-945 p. |
| Other physical details | digital |
| 500 ## - GENERAL NOTE | |
| General note | Publication Type: Journal Article |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Administration, Oral |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Animals |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Diabetes Mellitus, Type 2 |
| General subdivision | drug therapy |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Dogs |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Drug Discovery |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Humans |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Hypoglycemic Agents |
| General subdivision | administration & dosage |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Male |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Pyridines |
| General subdivision | administration & dosage |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Rats |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Receptors, G-Protein-Coupled |
| General subdivision | agonists |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Structure-Activity Relationship |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Triazoles |
| General subdivision | administration & dosage |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Maiti, Pranab |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Warshawsky, Alan M |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | DeBaillie, Amy C |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Otto, Keith A |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Wilbur, Kelly L |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Kahl, Steven D |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Patel Lewis, Anjana |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Cardona, Guemalli R |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Zink, Richard W |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Chen, Keyue |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Cr, Siddaramaiah |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Lineswala, Jayana P |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Neathery, Grace L |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Bouaichi, Cecilia |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Diseroad, Benjamin A |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Campbell, Alison N |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Sweetana, Stephanie A |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Adams, Lisa A |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Cabrera, Over |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ma, Xiaosu |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Yumibe, Nathan P |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Montrose-Rafizadeh, Chahrzad |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Chen, Yanyun |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Miller, Anne Reifel |
| 773 0# - HOST ITEM ENTRY | |
| Title | Journal of medicinal chemistry |
| Related parts | vol. 61 |
| -- | no. 3 |
| -- | p. 934-945 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://doi.org/10.1021/acs.jmedchem.7b01411">https://doi.org/10.1021/acs.jmedchem.7b01411</a> |
| Public note | Available from publisher's website |
No items available.