Preventing cognitive decline and dementia from cerebral small vessel disease: The LACI-1 Trial. Protocol and statistical analysis plan of a phase IIa dose escalation trial testing tolerability, safety and effect on intermediary endpoints of isosorbide mononitrate and cilostazol, separately and in combination. (Record no. 27561004)
[ view plain ]
| 000 -LEADER | |
|---|---|
| fixed length control field | 02316 a2200577 4500 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250517173531.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 201905s 0 0 eng d |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER | |
| International Standard Serial Number | 1747-4949 |
| 024 7# - OTHER STANDARD IDENTIFIER | |
| Standard number or code | 10.1177/1747493017731947 |
| Source of number or code | doi |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | NLM |
| Language of cataloging | eng |
| Transcribing agency | NLM |
| 100 1# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Blair, Gordon W |
| 264 #0 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Date of production, publication, distribution, manufacture, or copyright notice | 20190506 |
| 245 00 - TITLE STATEMENT | |
| Title | Preventing cognitive decline and dementia from cerebral small vessel disease: The LACI-1 Trial. Protocol and statistical analysis plan of a phase IIa dose escalation trial testing tolerability, safety and effect on intermediary endpoints of isosorbide mononitrate and cilostazol, separately and in combination. |
| Medium | [electronic resource] |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Name of publisher, distributor, etc. | International journal of stroke : official journal of the International Stroke Society |
| Date of publication, distribution, etc. | 07 2018 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 530-538 p. |
| Other physical details | digital |
| 500 ## - GENERAL NOTE | |
| General note | Publication Type: Clinical Trial, Phase II; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Age Factors |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Cerebral Small Vessel Diseases |
| General subdivision | complications |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Cilostazol |
| General subdivision | therapeutic use |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Cognition Disorders |
| General subdivision | etiology |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Dementia |
| General subdivision | etiology |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Double-Blind Method |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Female |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Follow-Up Studies |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Humans |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Isosorbide Dinitrate |
| General subdivision | analogs & derivatives |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Magnetic Resonance Imaging |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Male |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Neuropsychological Tests |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Severity of Illness Index |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Treatment Outcome |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | United Kingdom |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Vasodilator Agents |
| General subdivision | therapeutic use |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Appleton, Jason P |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Law, Zhe Kang |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Doubal, Fergus |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Flaherty, Katie |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Dooley, Richard |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Shuler, Kirsten |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Richardson, Carla |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Hamilton, Iona |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Shi, Yulu |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Stringer, Michael |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Boyd, Julia |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Thrippleton, Michael J |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Sprigg, Nikola |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Bath, Philip M |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Wardlaw, Joanna M |
| 773 0# - HOST ITEM ENTRY | |
| Title | International journal of stroke : official journal of the International Stroke Society |
| Related parts | vol. 13 |
| -- | no. 5 |
| -- | p. 530-538 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://doi.org/10.1177/1747493017731947">https://doi.org/10.1177/1747493017731947</a> |
| Public note | Available from publisher's website |
No items available.