Combination therapy with potent PI3K and MAPK inhibitors overcomes adaptive kinome resistance to single agents in preclinical models of glioblastoma. (Record no. 27051649)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02164 a2200649 4500 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250517145835.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 201806s 0 0 eng d |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER | |
| International Standard Serial Number | 1523-5866 |
| 024 7# - OTHER STANDARD IDENTIFIER | |
| Standard number or code | 10.1093/neuonc/nox044 |
| Source of number or code | doi |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | NLM |
| Language of cataloging | eng |
| Transcribing agency | NLM |
| 100 1# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | McNeill, Robert S |
| 264 #0 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Date of production, publication, distribution, manufacture, or copyright notice | 20180627 |
| 245 00 - TITLE STATEMENT | |
| Title | Combination therapy with potent PI3K and MAPK inhibitors overcomes adaptive kinome resistance to single agents in preclinical models of glioblastoma. |
| Medium | [electronic resource] |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Name of publisher, distributor, etc. | Neuro-oncology |
| Date of publication, distribution, etc. | Oct 2017 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 1469-1480 p. |
| Other physical details | digital |
| 500 ## - GENERAL NOTE | |
| General note | Publication Type: Journal Article |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Animals |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Apoptosis |
| General subdivision | drug effects |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Brain Neoplasms |
| General subdivision | drug therapy |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Cell Proliferation |
| General subdivision | drug effects |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Drug Resistance, Neoplasm |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Drug Synergism |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Glioblastoma |
| General subdivision | drug therapy |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Humans |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Mice |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Mitogen-Activated Protein Kinases |
| General subdivision | antagonists & inhibitors |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Phosphoinositide-3 Kinase Inhibitors |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Phosphorylation |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Protein Kinase Inhibitors |
| General subdivision | pharmacology |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Signal Transduction |
| General subdivision | drug effects |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Tumor Cells, Cultured |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Xenograft Model Antitumor Assays |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Canoutas, Demitra A |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Stuhlmiller, Timothy J |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Dhruv, Harshil D |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Irvin, David M |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Bash, Ryan E |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Angus, Steven P |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Herring, Laura E |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Simon, Jeremy M |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Skinner, Kasey R |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Limas, Juanita C |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Chen, Xin |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Schmid, Ralf S |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Siegel, Marni B |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Van Swearingen, Amanda E D |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Hadler, Michael J |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Sulman, Erik P |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Sarkaria, Jann N |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Anders, Carey K |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Graves, Lee M |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Berens, Michael E |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Johnson, Gary L |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Miller, C Ryan |
| 773 0# - HOST ITEM ENTRY | |
| Title | Neuro-oncology |
| Related parts | vol. 19 |
| -- | no. 11 |
| -- | p. 1469-1480 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://doi.org/10.1093/neuonc/nox044">https://doi.org/10.1093/neuonc/nox044</a> |
| Public note | Available from publisher's website |
No items available.