Investigations on the 4-Quinolone-3-carboxylic Acid Motif. 7. Synthesis and Pharmacological Evaluation of 4-Quinolone-3-carboxamides and 4-Hydroxy-2-quinolone-3-carboxamides as High Affinity Cannabinoid Receptor 2 (CB2R) Ligands with Improved Aqueous Solubility. (Record no. 25621178)

MARC details
000 -LEADER
fixed length control field 01761 a2200469 4500
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20250517073233.0
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 201607s 0 0 eng d
022 ## - INTERNATIONAL STANDARD SERIAL NUMBER
International Standard Serial Number 1520-4804
024 7# - OTHER STANDARD IDENTIFIER
Standard number or code 10.1021/acs.jmedchem.5b01559
Source of number or code doi
040 ## - CATALOGING SOURCE
Original cataloging agency NLM
Language of cataloging eng
Transcribing agency NLM
100 1# - MAIN ENTRY--PERSONAL NAME
Personal name Mugnaini, Claudia
264 #0 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE
Date of production, publication, distribution, manufacture, or copyright notice 20160712
245 00 - TITLE STATEMENT
Title Investigations on the 4-Quinolone-3-carboxylic Acid Motif. 7. Synthesis and Pharmacological Evaluation of 4-Quinolone-3-carboxamides and 4-Hydroxy-2-quinolone-3-carboxamides as High Affinity Cannabinoid Receptor 2 (CB2R) Ligands with Improved Aqueous Solubility.
Medium [electronic resource]
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Name of publisher, distributor, etc. Journal of medicinal chemistry
Date of publication, distribution, etc. Feb 2016
300 ## - PHYSICAL DESCRIPTION
Extent 1052-67 p.
Other physical details digital
500 ## - GENERAL NOTE
General note Publication Type: Journal Article; Research Support, Non-U.S. Gov't
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Animals
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Cell Survival
General subdivision drug effects
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Cells, Cultured
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Dose-Response Relationship, Drug
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Humans
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Ligands
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Mice
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Molecular Structure
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element NIH 3T3 Cells
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Quinolones
General subdivision chemical synthesis
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Receptor, Cannabinoid, CB2
General subdivision antagonists & inhibitors
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Solubility
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Structure-Activity Relationship
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Water
General subdivision chemistry
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Brizzi, Antonella
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Ligresti, Alessia
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Allarà, Marco
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Lamponi, Stefania
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Vacondio, Federica
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Silva, Claudia
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Mor, Marco
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Di Marzo, Vincenzo
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Corelli, Federico
773 0# - HOST ITEM ENTRY
Title Journal of medicinal chemistry
Related parts vol. 59
-- no. 3
-- p. 1052-67
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://doi.org/10.1021/acs.jmedchem.5b01559">https://doi.org/10.1021/acs.jmedchem.5b01559</a>
Public note Available from publisher's website

No items available.