Temporal pharmacokinetic/pharmacodynamic interaction between human CD3ε antigen-targeted monoclonal antibody otelixizumab and CD3ε binding and expression in human peripheral blood mononuclear cell static culture. (Record no. 25233646)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 01423 a2200349 4500 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250517051758.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 201601s 0 0 eng d |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER | |
| International Standard Serial Number | 1521-0103 |
| 024 7# - OTHER STANDARD IDENTIFIER | |
| Standard number or code | 10.1124/jpet.115.224899 |
| Source of number or code | doi |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | NLM |
| Language of cataloging | eng |
| Transcribing agency | NLM |
| 100 1# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Page, Kevin R |
| 264 #0 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Date of production, publication, distribution, manufacture, or copyright notice | 20160104 |
| 245 00 - TITLE STATEMENT | |
| Title | Temporal pharmacokinetic/pharmacodynamic interaction between human CD3ε antigen-targeted monoclonal antibody otelixizumab and CD3ε binding and expression in human peripheral blood mononuclear cell static culture. |
| Medium | [electronic resource] |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Name of publisher, distributor, etc. | The Journal of pharmacology and experimental therapeutics |
| Date of publication, distribution, etc. | Nov 2015 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 199-205 p. |
| Other physical details | digital |
| 500 ## - GENERAL NOTE | |
| General note | Publication Type: Journal Article |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Antibodies, Monoclonal, Humanized |
| General subdivision | pharmacokinetics |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | CD3 Complex |
| General subdivision | blood |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Cells, Cultured |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Humans |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Leukocytes, Mononuclear |
| General subdivision | drug effects |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Protein Binding |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Receptors, Antigen, T-Cell |
| General subdivision | metabolism |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Time Factors |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mezzalana, Enrica |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | MacDonald, Alexander J |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Zamuner, Stefano |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | De Nicolao, Giuseppe |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | van Maurik, Andre |
| 773 0# - HOST ITEM ENTRY | |
| Title | The Journal of pharmacology and experimental therapeutics |
| Related parts | vol. 355 |
| -- | no. 2 |
| -- | p. 199-205 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://doi.org/10.1124/jpet.115.224899">https://doi.org/10.1124/jpet.115.224899</a> |
| Public note | Available from publisher's website |
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