The discovery and characterization of the α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor potentiator N-{(3S,4S)-4-[4-(5-cyano-2-thienyl)phenoxy]tetrahydrofuran-3-yl}propane-2-sulfonamide (PF-04958242). (Record no. 24835357)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02589 a2200805 4500 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250517030407.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 201509s 0 0 eng d |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER | |
| International Standard Serial Number | 1520-4804 |
| 024 7# - OTHER STANDARD IDENTIFIER | |
| Standard number or code | 10.1021/acs.jmedchem.5b00300 |
| Source of number or code | doi |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | NLM |
| Language of cataloging | eng |
| Transcribing agency | NLM |
| 100 1# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Shaffer, Christopher L |
| 264 #0 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Date of production, publication, distribution, manufacture, or copyright notice | 20150904 |
| 245 00 - TITLE STATEMENT | |
| Title | The discovery and characterization of the α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor potentiator N-{(3S,4S)-4-[4-(5-cyano-2-thienyl)phenoxy]tetrahydrofuran-3-yl}propane-2-sulfonamide (PF-04958242). |
| Medium | [electronic resource] |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Name of publisher, distributor, etc. | Journal of medicinal chemistry |
| Date of publication, distribution, etc. | May 2015 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 4291-308 p. |
| Other physical details | digital |
| 500 ## - GENERAL NOTE | |
| General note | Publication Type: Journal Article |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Administration, Oral |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Adolescent |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Adult |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Aged |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Animals |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Binding Sites |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Disease Models, Animal |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Dogs |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Dose-Response Relationship, Drug |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Drug Discovery |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Drug Evaluation, Preclinical |
| General subdivision | methods |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Drug Stability |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Female |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Humans |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Male |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Memory, Short-Term |
| General subdivision | drug effects |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Mice, Inbred C57BL |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Middle Aged |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Protein Conformation |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Rats, Sprague-Dawley |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Receptors, AMPA |
| General subdivision | metabolism |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Schizophrenia |
| General subdivision | drug therapy |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Structure-Activity Relationship |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Sulfonamides |
| General subdivision | chemistry |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Thiophenes |
| General subdivision | chemistry |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Young Adult |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Patel, Nandini C |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Schwarz, Jacob |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Scialis, Renato J |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Wei, Yunjing |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Hou, Xinjun J |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Xie, Longfei |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Karki, Kapil |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Bryce, Dianne K |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Osgood, Sarah M |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Hoffmann, William E |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Lazzaro, John T |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Chang, Cheng |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | McGinnis, Dina F |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Lotarski, Susan M |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Liu, JianHua |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Obach, R Scott |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Weber, Mark L |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Chen, Laigao |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Zasadny, Kenneth R |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Seymour, Patricia A |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Schmidt, Christopher J |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Hajós, Mihály |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Hurst, Raymond S |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Pandit, Jayvardhan |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | O'Donnell, Christopher J |
| 773 0# - HOST ITEM ENTRY | |
| Title | Journal of medicinal chemistry |
| Related parts | vol. 58 |
| -- | no. 10 |
| -- | p. 4291-308 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://doi.org/10.1021/acs.jmedchem.5b00300">https://doi.org/10.1021/acs.jmedchem.5b00300</a> |
| Public note | Available from publisher's website |
No items available.