First-in-human study of CH5132799, an oral class I PI3K inhibitor, studying toxicity, pharmacokinetics, and pharmacodynamics, in patients with metastatic cancer. (Record no. 24200196)
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000 -LEADER | |
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fixed length control field | 02274 a2200637 4500 |
005 - DATE AND TIME OF LATEST TRANSACTION | |
control field | 20250516233615.0 |
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
fixed length control field | 201507s 0 0 eng d |
022 ## - INTERNATIONAL STANDARD SERIAL NUMBER | |
International Standard Serial Number | 1557-3265 |
024 7# - OTHER STANDARD IDENTIFIER | |
Standard number or code | 10.1158/1078-0432.CCR-14-1315 |
Source of number or code | doi |
040 ## - CATALOGING SOURCE | |
Original cataloging agency | NLM |
Language of cataloging | eng |
Transcribing agency | NLM |
100 1# - MAIN ENTRY--PERSONAL NAME | |
Personal name | Blagden, Sarah |
264 #0 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
Date of production, publication, distribution, manufacture, or copyright notice | 20150728 |
245 00 - TITLE STATEMENT | |
Title | First-in-human study of CH5132799, an oral class I PI3K inhibitor, studying toxicity, pharmacokinetics, and pharmacodynamics, in patients with metastatic cancer. |
Medium | [electronic resource] |
260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
Name of publisher, distributor, etc. | Clinical cancer research : an official journal of the American Association for Cancer Research |
Date of publication, distribution, etc. | Dec 2014 |
300 ## - PHYSICAL DESCRIPTION | |
Extent | 5908-17 p. |
Other physical details | digital |
500 ## - GENERAL NOTE | |
General note | Publication Type: Clinical Trial, Phase I; Journal Article; Research Support, Non-U.S. Gov't |
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
Topical term or geographic name entry element | Administration, Oral |
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
Topical term or geographic name entry element | Adult |
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
Topical term or geographic name entry element | Aged |
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
Topical term or geographic name entry element | Antineoplastic Agents |
General subdivision | pharmacology |
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
Topical term or geographic name entry element | Class I Phosphatidylinositol 3-Kinases |
General subdivision | antagonists & inhibitors |
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
Topical term or geographic name entry element | Dose-Response Relationship, Drug |
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
Topical term or geographic name entry element | Female |
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
Topical term or geographic name entry element | Humans |
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
Topical term or geographic name entry element | Male |
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
Topical term or geographic name entry element | Maximum Tolerated Dose |
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
Topical term or geographic name entry element | Middle Aged |
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
Topical term or geographic name entry element | Neoplasm Metastasis |
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
Topical term or geographic name entry element | Neoplasms |
General subdivision | diagnosis |
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
Topical term or geographic name entry element | Positron-Emission Tomography |
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
Topical term or geographic name entry element | Pyrimidines |
General subdivision | pharmacology |
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
Topical term or geographic name entry element | Sulfonamides |
General subdivision | pharmacology |
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
Topical term or geographic name entry element | Tomography, X-Ray Computed |
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
Topical term or geographic name entry element | Treatment Outcome |
700 1# - ADDED ENTRY--PERSONAL NAME | |
Personal name | Omlin, Aurelius |
700 1# - ADDED ENTRY--PERSONAL NAME | |
Personal name | Olmin, Aurelius |
700 1# - ADDED ENTRY--PERSONAL NAME | |
Personal name | Josephs, Debra |
700 1# - ADDED ENTRY--PERSONAL NAME | |
Personal name | Stavraka, Chara |
700 1# - ADDED ENTRY--PERSONAL NAME | |
Personal name | Zivi, Andrea |
700 1# - ADDED ENTRY--PERSONAL NAME | |
Personal name | Pinato, David J |
700 1# - ADDED ENTRY--PERSONAL NAME | |
Personal name | Anthoney, Alan |
700 1# - ADDED ENTRY--PERSONAL NAME | |
Personal name | Decordova, Shaun |
700 1# - ADDED ENTRY--PERSONAL NAME | |
Personal name | Swales, Karen |
700 1# - ADDED ENTRY--PERSONAL NAME | |
Personal name | Riisnaes, Ruth |
700 1# - ADDED ENTRY--PERSONAL NAME | |
Personal name | Pope, Lorna |
700 1# - ADDED ENTRY--PERSONAL NAME | |
Personal name | Noguchi, Kohei |
700 1# - ADDED ENTRY--PERSONAL NAME | |
Personal name | Shiokawa, Rie |
700 1# - ADDED ENTRY--PERSONAL NAME | |
Personal name | Inatani, Michiyasu |
700 1# - ADDED ENTRY--PERSONAL NAME | |
Personal name | Prince, Jenny |
700 1# - ADDED ENTRY--PERSONAL NAME | |
Personal name | Jones, Keith |
700 1# - ADDED ENTRY--PERSONAL NAME | |
Personal name | Twelves, Chris |
700 1# - ADDED ENTRY--PERSONAL NAME | |
Personal name | Spicer, James |
700 1# - ADDED ENTRY--PERSONAL NAME | |
Personal name | Banerji, Udai |
773 0# - HOST ITEM ENTRY | |
Title | Clinical cancer research : an official journal of the American Association for Cancer Research |
Related parts | vol. 20 |
-- | no. 23 |
-- | p. 5908-17 |
856 40 - ELECTRONIC LOCATION AND ACCESS | |
Uniform Resource Identifier | <a href="https://doi.org/10.1158/1078-0432.CCR-14-1315">https://doi.org/10.1158/1078-0432.CCR-14-1315</a> |
Public note | Available from publisher's website |
No items available.