Modeling, synthesis, and biological evaluation of potential retinoid X receptor (RXR) selective agonists: novel analogues of 4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydro-2-naphthyl)ethynyl]benzoic acid (bexarotene) and (E)-3-(3-(1,2,3,4-tetrahydro-1,1,4,4,6-pentamethylnaphthalen-7-yl)-4-hydroxyphenyl)acrylic acid (CD3254). (Record no. 23221619)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02145 a2200565 4500 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250516175957.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 201403s 0 0 eng d |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER | |
| International Standard Serial Number | 1520-4804 |
| 024 7# - OTHER STANDARD IDENTIFIER | |
| Standard number or code | 10.1021/jm4008517 |
| Source of number or code | doi |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | NLM |
| Language of cataloging | eng |
| Transcribing agency | NLM |
| 100 1# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Jurutka, Peter W |
| 264 #0 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Date of production, publication, distribution, manufacture, or copyright notice | 20140318 |
| 245 00 - TITLE STATEMENT | |
| Title | Modeling, synthesis, and biological evaluation of potential retinoid X receptor (RXR) selective agonists: novel analogues of 4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydro-2-naphthyl)ethynyl]benzoic acid (bexarotene) and (E)-3-(3-(1,2,3,4-tetrahydro-1,1,4,4,6-pentamethylnaphthalen-7-yl)-4-hydroxyphenyl)acrylic acid (CD3254). |
| Medium | [electronic resource] |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Name of publisher, distributor, etc. | Journal of medicinal chemistry |
| Date of publication, distribution, etc. | Nov 2013 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 8432-54 p. |
| Other physical details | digital |
| 500 ## - GENERAL NOTE | |
| General note | Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Coumaric Acids |
| General subdivision | chemical synthesis |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Crystallography, X-Ray |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Dose-Response Relationship, Drug |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Humans |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Models, Molecular |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Molecular Structure |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Retinoid X Receptors |
| General subdivision | agonists |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Structure-Activity Relationship |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Tetrahydronaphthalenes |
| General subdivision | chemical synthesis |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Kaneko, Ichiro |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Yang, Joanna |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Bhogal, Jaskaran S |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Swierski, Johnathon C |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Tabacaru, Christa R |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Montano, Luis A |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Huynh, Chanh C |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Jama, Rabia A |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mahelona, Ryan D |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Sarnowski, Joseph T |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Marcus, Lisa M |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Quezada, Alexis |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Lemming, Brittney |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Tedesco, Maria A |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Fischer, Audra J |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mohamed, Said A |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ziller, Joseph W |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ma, Ning |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Gray, Geoffrey M |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | van der Vaart, Arjan |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Marshall, Pamela A |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Wagner, Carl E |
| 773 0# - HOST ITEM ENTRY | |
| Title | Journal of medicinal chemistry |
| Related parts | vol. 56 |
| -- | no. 21 |
| -- | p. 8432-54 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://doi.org/10.1021/jm4008517">https://doi.org/10.1021/jm4008517</a> |
| Public note | Available from publisher's website |
No items available.