Discovery of a highly potent, nonabsorbable apical sodium-dependent bile acid transporter inhibitor (GSK2330672) for treatment of type 2 diabetes. (Record no. 22755864)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02176 a2200685 4500 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250516151359.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 201309s 0 0 eng d |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER | |
| International Standard Serial Number | 1520-4804 |
| 024 7# - OTHER STANDARD IDENTIFIER | |
| Standard number or code | 10.1021/jm400459m |
| Source of number or code | doi |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | NLM |
| Language of cataloging | eng |
| Transcribing agency | NLM |
| 100 1# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Wu, Yulin |
| 264 #0 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Date of production, publication, distribution, manufacture, or copyright notice | 20130903 |
| 245 00 - TITLE STATEMENT | |
| Title | Discovery of a highly potent, nonabsorbable apical sodium-dependent bile acid transporter inhibitor (GSK2330672) for treatment of type 2 diabetes. |
| Medium | [electronic resource] |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Name of publisher, distributor, etc. | Journal of medicinal chemistry |
| Date of publication, distribution, etc. | Jun 2013 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 5094-114 p. |
| Other physical details | digital |
| 500 ## - GENERAL NOTE | |
| General note | Publication Type: Journal Article |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Animals |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Bile Acids and Salts |
| General subdivision | metabolism |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Diabetes Mellitus, Type 2 |
| General subdivision | drug therapy |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Dogs |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Drug Discovery |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Drug Stability |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | HEK293 Cells |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Humans |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Hypoglycemic Agents |
| General subdivision | chemistry |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Male |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Methylamines |
| General subdivision | chemistry |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Mice |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Organic Anion Transporters, Sodium-Dependent |
| General subdivision | antagonists & inhibitors |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Rats |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Solubility |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Symporters |
| General subdivision | antagonists & inhibitors |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Thiazepines |
| General subdivision | chemistry |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Aquino, Christopher J |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Cowan, David J |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Anderson, Don L |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ambroso, Jeff L |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Bishop, Michael J |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Boros, Eric E |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Chen, Lihong |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Cunningham, Alan |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Dobbins, Robert L |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Feldman, Paul L |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Harston, Lindsey T |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Kaldor, Istvan W |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Klein, Ryan |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Liang, Xi |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | McIntyre, Maggie S |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Merrill, Christine L |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Patterson, Kristin M |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Prescott, Judith S |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ray, John S |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Roller, Shane G |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Yao, Xiaozhou |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Young, Andrew |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Yuen, Josephine |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Collins, Jon L |
| 773 0# - HOST ITEM ENTRY | |
| Title | Journal of medicinal chemistry |
| Related parts | vol. 56 |
| -- | no. 12 |
| -- | p. 5094-114 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://doi.org/10.1021/jm400459m">https://doi.org/10.1021/jm400459m</a> |
| Public note | Available from publisher's website |
No items available.