An abundance of rare functional variants in 202 drug target genes sequenced in 14,002 people. (Record no. 21790946)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02497 a2200805 4500 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250516092829.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 201207s 0 0 eng d |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER | |
| International Standard Serial Number | 1095-9203 |
| 024 7# - OTHER STANDARD IDENTIFIER | |
| Standard number or code | 10.1126/science.1217876 |
| Source of number or code | doi |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | NLM |
| Language of cataloging | eng |
| Transcribing agency | NLM |
| 100 1# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Nelson, Matthew R |
| 264 #0 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Date of production, publication, distribution, manufacture, or copyright notice | 20120723 |
| 245 00 - TITLE STATEMENT | |
| Title | An abundance of rare functional variants in 202 drug target genes sequenced in 14,002 people. |
| Medium | [electronic resource] |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Name of publisher, distributor, etc. | Science (New York, N.Y.) |
| Date of publication, distribution, etc. | Jul 2012 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 100-4 p. |
| Other physical details | digital |
| 500 ## - GENERAL NOTE | |
| General note | Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Black or African American |
| General subdivision | genetics |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Asian People |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Disease |
| General subdivision | genetics |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Gene Frequency |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Genetic Association Studies |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Genetic Predisposition to Disease |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Genetic Variation |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Genome, Human |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Geography |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | High-Throughput Nucleotide Sequencing |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Humans |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Molecular Targeted Therapy |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Multifactorial Inheritance |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Mutation Rate |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Pharmacogenetics |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Phenotype |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Polymorphism, Single Nucleotide |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Population Growth |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Sample Size |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Selection, Genetic |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | White People |
| General subdivision | genetics |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Wegmann, Daniel |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ehm, Margaret G |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Kessner, Darren |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | St Jean, Pamela |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Verzilli, Claudio |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Shen, Judong |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Tang, Zhengzheng |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Bacanu, Silviu-Alin |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Fraser, Dana |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Warren, Liling |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Aponte, Jennifer |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Zawistowski, Matthew |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Liu, Xiao |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Zhang, Hao |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Zhang, Yong |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Li, Jun |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Li, Yun |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Li, Li |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Woollard, Peter |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Topp, Simon |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Hall, Matthew D |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Nangle, Keith |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Wang, Jun |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Abecasis, Gonçalo |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Cardon, Lon R |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Zöllner, Sebastian |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Whittaker, John C |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Chissoe, Stephanie L |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Novembre, John |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mooser, Vincent |
| 773 0# - HOST ITEM ENTRY | |
| Title | Science (New York, N.Y.) |
| Related parts | vol. 337 |
| -- | no. 6090 |
| -- | p. 100-4 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://doi.org/10.1126/science.1217876">https://doi.org/10.1126/science.1217876</a> |
| Public note | Available from publisher's website |
No items available.