An anti-PCSK9 antibody reduces LDL-cholesterol on top of a statin and suppresses hepatocyte SREBP-regulated genes. (Record no. 21564761)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 03188 a2200985 4500 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250516080807.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 201207s 0 0 eng d |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER | |
| International Standard Serial Number | 1449-2288 |
| 024 7# - OTHER STANDARD IDENTIFIER | |
| Standard number or code | 10.7150/ijbs.3524 |
| Source of number or code | doi |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | NLM |
| Language of cataloging | eng |
| Transcribing agency | NLM |
| 100 1# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Zhang, Liwen |
| 264 #0 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Date of production, publication, distribution, manufacture, or copyright notice | 20120717 |
| 245 00 - TITLE STATEMENT | |
| Title | An anti-PCSK9 antibody reduces LDL-cholesterol on top of a statin and suppresses hepatocyte SREBP-regulated genes. |
| Medium | [electronic resource] |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Name of publisher, distributor, etc. | International journal of biological sciences |
| Date of publication, distribution, etc. | 2012 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 310-27 p. |
| Other physical details | digital |
| 500 ## - GENERAL NOTE | |
| General note | Publication Type: Journal Article |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Animals |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Antibodies, Monoclonal |
| General subdivision | pharmacology |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Antibody Affinity |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Anticholesteremic Agents |
| General subdivision | administration & dosage |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Cells, Cultured |
| General subdivision | drug effects |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Cholesterol Ester Transfer Proteins |
| General subdivision | genetics |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Cholesterol, LDL |
| General subdivision | blood |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Gene Expression Profiling |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Gene Expression Regulation |
| General subdivision | drug effects |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Hep G2 Cells |
| General subdivision | drug effects |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Hepatocytes |
| General subdivision | drug effects |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Humans |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Immunization, Passive |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Lipid Metabolism |
| General subdivision | genetics |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Liver |
| General subdivision | drug effects |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Macaca mulatta |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Metabolic Syndrome |
| General subdivision | drug therapy |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Mice |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Mice, Transgenic |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Proprotein Convertase 9 |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Proprotein Convertases |
| General subdivision | antagonists & inhibitors |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | RNA, Messenger |
| General subdivision | metabolism |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Receptors, LDL |
| General subdivision | biosynthesis |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Recombinant Proteins |
| General subdivision | metabolism |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Serine Endopeptidases |
| General subdivision | biosynthesis |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Simvastatin |
| General subdivision | administration & dosage |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Sterol Regulatory Element Binding Proteins |
| General subdivision | physiology |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | McCabe, Timothy |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Condra, Jon H |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ni, Yan G |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Peterson, Laurence B |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Wang, Weirong |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Strack, Alison M |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Wang, Fubao |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Pandit, Shilpa |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Hammond, Holly |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Wood, Dana |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Lewis, Dale |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Rosa, Ray |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mendoza, Vivienne |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Cumiskey, Anne Marie |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Johns, Douglas G |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Hansen, Barbara C |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Shen, Xun |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Geoghagen, Neil |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Jensen, Kristian |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Zhu, Lei |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Wietecha, Karol |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Wisniewski, Douglas |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Huang, Lingyi |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Zhao, Jing Zhang |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ernst, Robin |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Hampton, Richard |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Haytko, Peter |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ansbro, Frances |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Chilewski, Shannon |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Chin, Jayne |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mitnaul, Lyndon J |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Pellacani, Andrea |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Sparrow, Carl P |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | An, Zhiqiang |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Strohl, William |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Hubbard, Brian |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Plump, Andrew S |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Blom, Daniel |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Sitlani, Ayesha |
| 773 0# - HOST ITEM ENTRY | |
| Title | International journal of biological sciences |
| Related parts | vol. 8 |
| -- | no. 3 |
| -- | p. 310-27 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://doi.org/10.7150/ijbs.3524">https://doi.org/10.7150/ijbs.3524</a> |
| Public note | Available from publisher's website |
No items available.