First and second generation γ-secretase modulators (GSMs) modulate amyloid-β (Aβ) peptide production through different mechanisms. (Record no. 21545575)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02745 a2200829 4500 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250516080148.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 201206s 0 0 eng d |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER | |
| International Standard Serial Number | 1083-351X |
| 024 7# - OTHER STANDARD IDENTIFIER | |
| Standard number or code | 10.1074/jbc.M111.305227 |
| Source of number or code | doi |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | NLM |
| Language of cataloging | eng |
| Transcribing agency | NLM |
| 100 1# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Borgegard, Tomas |
| 264 #0 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Date of production, publication, distribution, manufacture, or copyright notice | 20120606 |
| 245 00 - TITLE STATEMENT | |
| Title | First and second generation γ-secretase modulators (GSMs) modulate amyloid-β (Aβ) peptide production through different mechanisms. |
| Medium | [electronic resource] |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Name of publisher, distributor, etc. | The Journal of biological chemistry |
| Date of publication, distribution, etc. | Apr 2012 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 11810-9 p. |
| Other physical details | digital |
| 500 ## - GENERAL NOTE | |
| General note | Publication Type: Journal Article |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Alanine |
| General subdivision | analogs & derivatives |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Amyloid Precursor Protein Secretases |
| General subdivision | antagonists & inhibitors |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Amyloid beta-Peptides |
| General subdivision | biosynthesis |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Amyloid beta-Protein Precursor |
| General subdivision | metabolism |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Animals |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Azepines |
| General subdivision | chemistry |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Binding, Competitive |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Brain |
| General subdivision | drug effects |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Carbamates |
| General subdivision | pharmacology |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Cell-Free System |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Dibenzazepines |
| General subdivision | pharmacology |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Dipeptides |
| General subdivision | pharmacology |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Drug Interactions |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Female |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Flurbiprofen |
| General subdivision | pharmacology |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Guinea Pigs |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | HEK293 Cells |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Humans |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Imidazoles |
| General subdivision | pharmacology |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Mice |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Mice, Inbred C57BL |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Piperidines |
| General subdivision | pharmacology |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Protein Binding |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Protein Processing, Post-Translational |
| General subdivision | drug effects |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Pyrans |
| General subdivision | chemistry |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Pyridines |
| General subdivision | chemistry |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Pyrimidines |
| General subdivision | chemistry |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Rats |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Receptor, EphA4 |
| General subdivision | metabolism |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Receptor, EphB2 |
| General subdivision | metabolism |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Receptors, Notch |
| General subdivision | metabolism |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Sulfonamides |
| General subdivision | pharmacology |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Sulindac |
| General subdivision | analogs & derivatives |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Juréus, Anders |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Olsson, Fredrik |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Rosqvist, Susanne |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Sabirsh, Alan |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Rotticci, Didier |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Paulsen, Kim |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Klintenberg, Rebecka |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Yan, Hongmei |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Waldman, Magnus |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Stromberg, Kia |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Nord, Johan |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Johansson, Jonas |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Regner, Anna |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Parpal, Santiago |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Malinowsky, David |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Radesater, Ann-Cathrin |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Li, Tingsheng |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Singh, Rajeshwar |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Eriksson, Hakan |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Lundkvist, Johan |
| 773 0# - HOST ITEM ENTRY | |
| Title | The Journal of biological chemistry |
| Related parts | vol. 287 |
| -- | no. 15 |
| -- | p. 11810-9 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://doi.org/10.1074/jbc.M111.305227">https://doi.org/10.1074/jbc.M111.305227</a> |
| Public note | Available from publisher's website |
No items available.