Which compound to select in lead optimization? Prospectively validated proteochemometric models guide preclinical development. (Record no. 21357548)

MARC details
000 -LEADER
fixed length control field 01560 a2200445 4500
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20250516065542.0
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 201204s 0 0 eng d
022 ## - INTERNATIONAL STANDARD SERIAL NUMBER
International Standard Serial Number 1932-6203
024 7# - OTHER STANDARD IDENTIFIER
Standard number or code 10.1371/journal.pone.0027518
Source of number or code doi
040 ## - CATALOGING SOURCE
Original cataloging agency NLM
Language of cataloging eng
Transcribing agency NLM
100 1# - MAIN ENTRY--PERSONAL NAME
Personal name van Westen, Gerard J P
264 #0 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE
Date of production, publication, distribution, manufacture, or copyright notice 20120402
245 00 - TITLE STATEMENT
Title Which compound to select in lead optimization? Prospectively validated proteochemometric models guide preclinical development.
Medium [electronic resource]
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Name of publisher, distributor, etc. PloS one
Date of publication, distribution, etc. 2011
300 ## - PHYSICAL DESCRIPTION
Extent e27518 p.
Other physical details digital
500 ## - GENERAL NOTE
General note Publication Type: Journal Article; Research Support, Non-U.S. Gov't
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Amino Acid Sequence
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Binding Sites
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Databases as Topic
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Drug Evaluation, Preclinical
General subdivision methods
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element HIV Reverse Transcriptase
General subdivision antagonists & inhibitors
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Humans
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Ligands
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Models, Molecular
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Molecular Sequence Data
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Mutation
General subdivision genetics
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Proteomics
General subdivision methods
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Reproducibility of Results
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Reverse Transcriptase Inhibitors
General subdivision analysis
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Wegner, Jörg K
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Geluykens, Peggy
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Kwanten, Leen
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Vereycken, Inge
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Peeters, Anik
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Ijzerman, Adriaan P
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name van Vlijmen, Herman W T
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Bender, Andreas
773 0# - HOST ITEM ENTRY
Title PloS one
Related parts vol. 6
-- no. 11
-- p. e27518
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://doi.org/10.1371/journal.pone.0027518">https://doi.org/10.1371/journal.pone.0027518</a>
Public note Available from publisher's website

No items available.