Design, synthesis, biological activity, and ADME properties of pyrazolo[3,4-d]pyrimidines active in hypoxic human leukemia cells: a lead optimization study. (Record no. 20712602)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 01754 a2200505 4500 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250516031532.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 201107s 0 0 eng d |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER | |
| International Standard Serial Number | 1520-4804 |
| 024 7# - OTHER STANDARD IDENTIFIER | |
| Standard number or code | 10.1021/jm1012819 |
| Source of number or code | doi |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | NLM |
| Language of cataloging | eng |
| Transcribing agency | NLM |
| 100 1# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Radi, Marco |
| 264 #0 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Date of production, publication, distribution, manufacture, or copyright notice | 20110704 |
| 245 00 - TITLE STATEMENT | |
| Title | Design, synthesis, biological activity, and ADME properties of pyrazolo[3,4-d]pyrimidines active in hypoxic human leukemia cells: a lead optimization study. |
| Medium | [electronic resource] |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Name of publisher, distributor, etc. | Journal of medicinal chemistry |
| Date of publication, distribution, etc. | Apr 2011 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 2610-26 p. |
| Other physical details | digital |
| 500 ## - GENERAL NOTE | |
| General note | Publication Type: Journal Article; Research Support, Non-U.S. Gov't |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Antineoplastic Agents |
| General subdivision | chemical synthesis |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Cell Hypoxia |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Cell Line, Tumor |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Drug Screening Assays, Antitumor |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Humans |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Leukemia |
| General subdivision | pathology |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Magnetic Resonance Spectroscopy |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Mass Spectrometry |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Models, Molecular |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Pyrazoles |
| General subdivision | chemical synthesis |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Pyrimidines |
| General subdivision | chemical synthesis |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Dreassi, Elena |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Brullo, Chiara |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Crespan, Emmanuele |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Tintori, Cristina |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Bernardo, Vincenzo |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Valoti, Massimo |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Zamperini, Claudio |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Daigl, Henry |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Musumeci, Francesca |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Carraro, Fabio |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Naldini, Antonella |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Filippi, Irene |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Maga, Giovanni |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Schenone, Silvia |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Botta, Maurizio |
| 773 0# - HOST ITEM ENTRY | |
| Title | Journal of medicinal chemistry |
| Related parts | vol. 54 |
| -- | no. 8 |
| -- | p. 2610-26 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://doi.org/10.1021/jm1012819">https://doi.org/10.1021/jm1012819</a> |
| Public note | Available from publisher's website |
No items available.