Acquired resistance to BRAF inhibitors mediated by a RAF kinase switch in melanoma can be overcome by cotargeting MEK and IGF-1R/PI3K. (Record no. 20445739)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02155 a2200589 4500 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250516014951.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 201101s 0 0 eng d |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER | |
| International Standard Serial Number | 1878-3686 |
| 024 7# - OTHER STANDARD IDENTIFIER | |
| Standard number or code | 10.1016/j.ccr.2010.11.023 |
| Source of number or code | doi |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | NLM |
| Language of cataloging | eng |
| Transcribing agency | NLM |
| 100 1# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Villanueva, Jessie |
| 264 #0 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Date of production, publication, distribution, manufacture, or copyright notice | 20110106 |
| 245 00 - TITLE STATEMENT | |
| Title | Acquired resistance to BRAF inhibitors mediated by a RAF kinase switch in melanoma can be overcome by cotargeting MEK and IGF-1R/PI3K. |
| Medium | [electronic resource] |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Name of publisher, distributor, etc. | Cancer cell |
| Date of publication, distribution, etc. | Dec 2010 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 683-95 p. |
| Other physical details | digital |
| 500 ## - GENERAL NOTE | |
| General note | Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Cell Line, Tumor |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Drug Resistance, Neoplasm |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Humans |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | MAP Kinase Signaling System |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Melanoma |
| General subdivision | drug therapy |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Mitogen-Activated Protein Kinase Kinases |
| General subdivision | antagonists & inhibitors |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Phosphatidylinositol 3-Kinases |
| General subdivision | physiology |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Phosphoinositide-3 Kinase Inhibitors |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Phosphorylation |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Proto-Oncogene Proteins B-raf |
| General subdivision | antagonists & inhibitors |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Proto-Oncogene Proteins c-akt |
| General subdivision | metabolism |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Receptor, IGF Type 1 |
| General subdivision | antagonists & inhibitors |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | raf Kinases |
| General subdivision | physiology |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Vultur, Adina |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Lee, John T |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Somasundaram, Rajasekharan |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Fukunaga-Kalabis, Mizuho |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Cipolla, Angela K |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Wubbenhorst, Bradley |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Xu, Xiaowei |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Gimotty, Phyllis A |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Kee, Damien |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Santiago-Walker, Ademi E |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Letrero, Richard |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | D'Andrea, Kurt |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Pushparajan, Anitha |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Hayden, James E |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Brown, Kimberly Dahlman |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Laquerre, Sylvie |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | McArthur, Grant A |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Sosman, Jeffrey A |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Nathanson, Katherine L |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Herlyn, Meenhard |
| 773 0# - HOST ITEM ENTRY | |
| Title | Cancer cell |
| Related parts | vol. 18 |
| -- | no. 6 |
| -- | p. 683-95 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://doi.org/10.1016/j.ccr.2010.11.023">https://doi.org/10.1016/j.ccr.2010.11.023</a> |
| Public note | Available from publisher's website |
No items available.