Discovery of a factor Xa inhibitor (3R,4R)-1-(2,2-difluoro-ethyl)-pyrrolidine-3,4-dicarboxylic acid 3-[(5-chloro-pyridin-2-yl)-amide] 4-[[2-fluoro-4-(2-oxo-2H-pyridin-1-yl)-phenyl]-amide] as a clinical candidate. (Record no. 19991372)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 01409 a2200385 4500 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250515232928.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 201012s 0 0 eng d |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER | |
| International Standard Serial Number | 1464-3405 |
| 024 7# - OTHER STANDARD IDENTIFIER | |
| Standard number or code | 10.1016/j.bmcl.2010.06.126 |
| Source of number or code | doi |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | NLM |
| Language of cataloging | eng |
| Transcribing agency | NLM |
| 100 1# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Anselm, Lilli |
| 264 #0 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Date of production, publication, distribution, manufacture, or copyright notice | 20101206 |
| 245 00 - TITLE STATEMENT | |
| Title | Discovery of a factor Xa inhibitor (3R,4R)-1-(2,2-difluoro-ethyl)-pyrrolidine-3,4-dicarboxylic acid 3-[(5-chloro-pyridin-2-yl)-amide] 4-[[2-fluoro-4-(2-oxo-2H-pyridin-1-yl)-phenyl]-amide] as a clinical candidate. |
| Medium | [electronic resource] |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Name of publisher, distributor, etc. | Bioorganic & medicinal chemistry letters |
| Date of publication, distribution, etc. | Sep 2010 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 5313-9 p. |
| Other physical details | digital |
| 500 ## - GENERAL NOTE | |
| General note | Publication Type: Journal Article |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Factor Xa Inhibitors |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Pyrrolidines |
| General subdivision | chemistry |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Banner, David W |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Benz, Jörg |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Zbinden, Katrin Groebke |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Himber, Jacques |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Hilpert, Hans |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Huber, Walter |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Kuhn, Bernd |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mary, Jean-Luc |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Otteneder, Michael B |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Panday, Narendra |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ricklin, Fabienne |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Stahl, Martin |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Thomi, Stefan |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Haap, Wolfgang |
| 773 0# - HOST ITEM ENTRY | |
| Title | Bioorganic & medicinal chemistry letters |
| Related parts | vol. 20 |
| -- | no. 17 |
| -- | p. 5313-9 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://doi.org/10.1016/j.bmcl.2010.06.126">https://doi.org/10.1016/j.bmcl.2010.06.126</a> |
| Public note | Available from publisher's website |
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