Carbonic anhydrase inhibitors. The X-ray crystal structure of human isoform II in adduct with an adamantyl analogue of acetazolamide resides in a less utilized binding pocket than most hydrophobic inhibitors. (Record no. 19951508)

MARC details
000 -LEADER
fixed length control field 01670 a2200409 4500
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20250515231619.0
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 201011s 0 0 eng d
022 ## - INTERNATIONAL STANDARD SERIAL NUMBER
International Standard Serial Number 1464-3405
024 7# - OTHER STANDARD IDENTIFIER
Standard number or code 10.1016/j.bmcl.2010.06.082
Source of number or code doi
040 ## - CATALOGING SOURCE
Original cataloging agency NLM
Language of cataloging eng
Transcribing agency NLM
100 1# - MAIN ENTRY--PERSONAL NAME
Personal name Avvaru, Balendu Sankara
264 #0 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE
Date of production, publication, distribution, manufacture, or copyright notice 20101123
245 00 - TITLE STATEMENT
Title Carbonic anhydrase inhibitors. The X-ray crystal structure of human isoform II in adduct with an adamantyl analogue of acetazolamide resides in a less utilized binding pocket than most hydrophobic inhibitors.
Medium [electronic resource]
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Name of publisher, distributor, etc. Bioorganic & medicinal chemistry letters
Date of publication, distribution, etc. Aug 2010
300 ## - PHYSICAL DESCRIPTION
Extent 4376-81 p.
Other physical details digital
500 ## - GENERAL NOTE
General note Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Acetazolamide
General subdivision analogs & derivatives
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Animals
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Binding Sites
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Carbonic Anhydrase II
General subdivision antagonists & inhibitors
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Carbonic Anhydrase Inhibitors
General subdivision chemistry
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Computer Simulation
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Crystallography, X-Ray
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Humans
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Hydrophobic and Hydrophilic Interactions
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Mice
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Protein Isoforms
General subdivision antagonists & inhibitors
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Sulfonamides
General subdivision chemistry
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Wagner, Jason M
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Maresca, Alfonso
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Scozzafava, Andrea
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Robbins, Arthur H
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Supuran, Claudiu T
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name McKenna, Robert
773 0# - HOST ITEM ENTRY
Title Bioorganic & medicinal chemistry letters
Related parts vol. 20
-- no. 15
-- p. 4376-81
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://doi.org/10.1016/j.bmcl.2010.06.082">https://doi.org/10.1016/j.bmcl.2010.06.082</a>
Public note Available from publisher's website

No items available.