The first-in-human study of the hydrogen sulfate (Hyd-sulfate) capsule of the MEK1/2 inhibitor AZD6244 (ARRY-142886): a phase I open-label multicenter trial in patients with advanced cancer. (Record no. 19548048)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02110 a2200541 4500 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250515210446.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 201005s 0 0 eng d |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER | |
| International Standard Serial Number | 1557-3265 |
| 024 7# - OTHER STANDARD IDENTIFIER | |
| Standard number or code | 10.1158/1078-0432.CCR-09-2483 |
| Source of number or code | doi |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | NLM |
| Language of cataloging | eng |
| Transcribing agency | NLM |
| 100 1# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Banerji, Udai |
| 264 #0 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Date of production, publication, distribution, manufacture, or copyright notice | 20100520 |
| 245 00 - TITLE STATEMENT | |
| Title | The first-in-human study of the hydrogen sulfate (Hyd-sulfate) capsule of the MEK1/2 inhibitor AZD6244 (ARRY-142886): a phase I open-label multicenter trial in patients with advanced cancer. |
| Medium | [electronic resource] |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Name of publisher, distributor, etc. | Clinical cancer research : an official journal of the American Association for Cancer Research |
| Date of publication, distribution, etc. | Mar 2010 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 1613-23 p. |
| Other physical details | digital |
| 500 ## - GENERAL NOTE | |
| General note | Publication Type: Clinical Trial, Phase I; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Administration, Oral |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Adult |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Aged |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Antineoplastic Agents |
| General subdivision | administration & dosage |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Benzimidazoles |
| General subdivision | administration & dosage |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Capsules |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Female |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Humans |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | MAP Kinase Kinase 1 |
| General subdivision | antagonists & inhibitors |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | MAP Kinase Kinase 2 |
| General subdivision | antagonists & inhibitors |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Male |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Maximum Tolerated Dose |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Middle Aged |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Neoplasms |
| General subdivision | drug therapy |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Camidge, D Ross |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Verheul, Henk M W |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Agarwal, Roshan |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Sarker, Debashis |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Kaye, Stan B |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Desar, Ingrid M E |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Timmer-Bonte, Johanna N H |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Eckhardt, S Gail |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Lewis, Karl D |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Brown, Kathryn H |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Cantarini, Mireille V |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Morris, Clive |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | George, Sarah M A |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Smith, Paul D |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | van Herpen, Carla M L |
| 773 0# - HOST ITEM ENTRY | |
| Title | Clinical cancer research : an official journal of the American Association for Cancer Research |
| Related parts | vol. 16 |
| -- | no. 5 |
| -- | p. 1613-23 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://doi.org/10.1158/1078-0432.CCR-09-2483">https://doi.org/10.1158/1078-0432.CCR-09-2483</a> |
| Public note | Available from publisher's website |
No items available.