Discovery of orally bioavailable 1,3,4-trisubstituted 2-oxopiperazine-based melanocortin-4 receptor agonists as potential antiobesity agents. (Record no. 18241068)

MARC details
000 -LEADER
fixed length control field 02055 a2200649 4500
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20250515134525.0
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 200810s 0 0 eng d
022 ## - INTERNATIONAL STANDARD SERIAL NUMBER
International Standard Serial Number 1520-4804
024 7# - OTHER STANDARD IDENTIFIER
Standard number or code 10.1021/jm800525p
Source of number or code doi
040 ## - CATALOGING SOURCE
Original cataloging agency NLM
Language of cataloging eng
Transcribing agency NLM
100 1# - MAIN ENTRY--PERSONAL NAME
Personal name Tian, Xinrong
264 #0 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE
Date of production, publication, distribution, manufacture, or copyright notice 20081030
245 00 - TITLE STATEMENT
Title Discovery of orally bioavailable 1,3,4-trisubstituted 2-oxopiperazine-based melanocortin-4 receptor agonists as potential antiobesity agents.
Medium [electronic resource]
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Name of publisher, distributor, etc. Journal of medicinal chemistry
Date of publication, distribution, etc. Oct 2008
300 ## - PHYSICAL DESCRIPTION
Extent 6055-66 p.
Other physical details digital
500 ## - GENERAL NOTE
General note Publication Type: Journal Article
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Administration, Oral
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Animals
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Anti-Obesity Agents
General subdivision chemistry
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Biological Availability
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Diet
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Disease Models, Animal
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Dogs
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Drug Design
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Drug Evaluation, Preclinical
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Eating
General subdivision drug effects
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Male
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Molecular Conformation
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Obesity
General subdivision drug therapy
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Piperazines
General subdivision chemistry
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Rats
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Receptor, Melanocortin, Type 4
General subdivision agonists
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Stereoisomerism
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Switzer, Adrian G
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Derose, Steve A
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Mishra, Rajesh K
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Solinsky, Mark G
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Mumin, Rashid N
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Ebetino, Frank H
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Jayasinghe, Lalith R
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Webster, Mark E
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Colson, Anny-Odile
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Crossdoersen, Doreen
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Pinney, Beth B
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Farmer, Julie A
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Dowty, Martin E
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Obringer, Cindy M
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Cruze, Charles A
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Burklow, Melissa L
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Suchanek, Paula M
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Dong, Lily
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Dirr, Mary Kay
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Sheldon, Russell J
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Wos, John A
773 0# - HOST ITEM ENTRY
Title Journal of medicinal chemistry
Related parts vol. 51
-- no. 19
-- p. 6055-66
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://doi.org/10.1021/jm800525p">https://doi.org/10.1021/jm800525p</a>
Public note Available from publisher's website

No items available.