Discovery of novel 2,3-diarylfuro[2,3-b]pyridin-4-amines as potent and selective inhibitors of Lck: synthesis, SAR, and pharmacokinetic properties. (Record no. 16837315)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 01771 a2200505 4500 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250515054859.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 200705s 0 0 eng d |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER | |
| International Standard Serial Number | 0960-894X |
| 024 7# - OTHER STANDARD IDENTIFIER | |
| Standard number or code | 10.1016/j.bmcl.2007.01.048 |
| Source of number or code | doi |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | NLM |
| Language of cataloging | eng |
| Transcribing agency | NLM |
| 100 1# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Martin, Matthew W |
| 264 #0 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Date of production, publication, distribution, manufacture, or copyright notice | 20070530 |
| 245 00 - TITLE STATEMENT | |
| Title | Discovery of novel 2,3-diarylfuro[2,3-b]pyridin-4-amines as potent and selective inhibitors of Lck: synthesis, SAR, and pharmacokinetic properties. |
| Medium | [electronic resource] |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Name of publisher, distributor, etc. | Bioorganic & medicinal chemistry letters |
| Date of publication, distribution, etc. | Apr 2007 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 2299-304 p. |
| Other physical details | digital |
| 500 ## - GENERAL NOTE | |
| General note | Publication Type: Journal Article |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Amines |
| General subdivision | chemical synthesis |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Animals |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Humans |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Inhibitory Concentration 50 |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Lymphocyte Specific Protein Tyrosine Kinase p56(lck) |
| General subdivision | antagonists & inhibitors |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Pharmacokinetics |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Protein Kinase Inhibitors |
| General subdivision | chemical synthesis |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Pyridines |
| General subdivision | chemical synthesis |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Rats |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Rats, Sprague-Dawley |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Structure-Activity Relationship |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Newcomb, John |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Nunes, Joseph J |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Bemis, Jean E |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | McGowan, David C |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | White, Ryan D |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Buchanan, John L |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | DiMauro, Erin F |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Boucher, Christina |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Faust, Theodore |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Hsieh, Faye |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Huang, Xin |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Lee, Josie H |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Schneider, Stephen |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Turci, Susan M |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Zhu, Xiaotian |
| 773 0# - HOST ITEM ENTRY | |
| Title | Bioorganic & medicinal chemistry letters |
| Related parts | vol. 17 |
| -- | no. 8 |
| -- | p. 2299-304 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://doi.org/10.1016/j.bmcl.2007.01.048">https://doi.org/10.1016/j.bmcl.2007.01.048</a> |
| Public note | Available from publisher's website |
No items available.