Discovery and SAR of isonicotinamide BACE-1 inhibitors that bind beta-secretase in a N-terminal 10s-loop down conformation. (Record no. 16819713)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02063 a2200589 4500 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250515054258.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 200705s 0 0 eng d |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER | |
| International Standard Serial Number | 0960-894X |
| 024 7# - OTHER STANDARD IDENTIFIER | |
| Standard number or code | 10.1016/j.bmcl.2006.12.051 |
| Source of number or code | doi |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | NLM |
| Language of cataloging | eng |
| Transcribing agency | NLM |
| 100 1# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Stauffer, Shaun R |
| 264 #0 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Date of production, publication, distribution, manufacture, or copyright notice | 20070529 |
| 245 00 - TITLE STATEMENT | |
| Title | Discovery and SAR of isonicotinamide BACE-1 inhibitors that bind beta-secretase in a N-terminal 10s-loop down conformation. |
| Medium | [electronic resource] |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Name of publisher, distributor, etc. | Bioorganic & medicinal chemistry letters |
| Date of publication, distribution, etc. | Mar 2007 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 1788-92 p. |
| Other physical details | digital |
| 500 ## - GENERAL NOTE | |
| General note | Publication Type: Journal Article |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Amyloid Precursor Protein Secretases |
| General subdivision | antagonists & inhibitors |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Animals |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Aspartic Acid Endopeptidases |
| General subdivision | antagonists & inhibitors |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Baculoviridae |
| General subdivision | drug effects |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Biological Availability |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Cells, Cultured |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Enzyme Inhibitors |
| General subdivision | chemical synthesis |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Magnetic Resonance Spectroscopy |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Models, Molecular |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Molecular Conformation |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Molecular Weight |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Niacinamide |
| General subdivision | chemical synthesis |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Rats |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Structure-Activity Relationship |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Stanton, Matthew G |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Gregro, Alison R |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Steinbeiser, Melissa A |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Shaffer, Jennifer R |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Nantermet, Philippe G |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Barrow, James C |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Rittle, Kenneth E |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Collusi, Dennis |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Espeseth, Amy S |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Lai, Ming-Tain |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Pietrak, Beth L |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Holloway, M Katharine |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | McGaughey, Georgia B |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Munshi, Sanjeev K |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Hochman, Jerome H |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Simon, Adam J |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Selnick, Harold G |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Graham, Samuel L |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Vacca, Joseph P |
| 773 0# - HOST ITEM ENTRY | |
| Title | Bioorganic & medicinal chemistry letters |
| Related parts | vol. 17 |
| -- | no. 6 |
| -- | p. 1788-92 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://doi.org/10.1016/j.bmcl.2006.12.051">https://doi.org/10.1016/j.bmcl.2006.12.051</a> |
| Public note | Available from publisher's website |
No items available.