Discovery of aminoquinazolines as potent, orally bioavailable inhibitors of Lck: synthesis, SAR, and in vivo anti-inflammatory activity. (Record no. 16552854)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02913 a2200937 4500 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250515041436.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 200610s 0 0 eng d |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER | |
| International Standard Serial Number | 0022-2623 |
| 024 7# - OTHER STANDARD IDENTIFIER | |
| Standard number or code | 10.1021/jm0605482 |
| Source of number or code | doi |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | NLM |
| Language of cataloging | eng |
| Transcribing agency | NLM |
| 100 1# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | DiMauro, Erin F |
| 264 #0 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Date of production, publication, distribution, manufacture, or copyright notice | 20061024 |
| 245 00 - TITLE STATEMENT | |
| Title | Discovery of aminoquinazolines as potent, orally bioavailable inhibitors of Lck: synthesis, SAR, and in vivo anti-inflammatory activity. |
| Medium | [electronic resource] |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Name of publisher, distributor, etc. | Journal of medicinal chemistry |
| Date of publication, distribution, etc. | Sep 2006 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 5671-86 p. |
| Other physical details | digital |
| 500 ## - GENERAL NOTE | |
| General note | Publication Type: Journal Article |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Administration, Oral |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Animals |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Anti-Inflammatory Agents, Non-Steroidal |
| General subdivision | chemical synthesis |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Benzamides |
| General subdivision | chemical synthesis |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Biological Availability |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Cell Proliferation |
| General subdivision | drug effects |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Cells, Cultured |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Female |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Humans |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | In Vitro Techniques |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Interleukin-2 |
| General subdivision | biosynthesis |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Lymphocyte Specific Protein Tyrosine Kinase p56(lck) |
| General subdivision | antagonists & inhibitors |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Male |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Mice |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Mice, Inbred BALB C |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Models, Molecular |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Quinazolines |
| General subdivision | chemical synthesis |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Rats |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Rats, Sprague-Dawley |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Structure-Activity Relationship |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | T-Lymphocytes |
| General subdivision | cytology |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Tumor Necrosis Factor-alpha |
| General subdivision | biosynthesis |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Newcomb, John |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Nunes, Joseph J |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Bemis, Jean E |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Boucher, Christina |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Buchanan, John L |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Buckner, William H |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Cee, Victor J |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Chai, Lilly |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Deak, Holly L |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Epstein, Linda F |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Faust, Ted |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Gallant, Paul |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Geuns-Meyer, Stephanie D |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Gore, Anu |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Gu, Yan |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Henkle, Brad |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Hodous, Brian L |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Hsieh, Faye |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Huang, Xin |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Kim, Joseph L |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Lee, Josie H |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Martin, Matthew W |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Masse, Craig E |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | McGowan, David C |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Metz, Daniela |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mohn, Deanna |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Morgenstern, Kurt A |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Oliveira-dos-Santos, Antonio |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Patel, Vinod F |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Powers, David |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Rose, Paul E |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Schneider, Stephen |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Tomlinson, Susan A |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Tudor, Yan-Yan |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Turci, Susan M |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Welcher, Andrew A |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | White, Ryan D |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Zhao, Huilin |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Zhu, Li |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Zhu, Xiaotian |
| 773 0# - HOST ITEM ENTRY | |
| Title | Journal of medicinal chemistry |
| Related parts | vol. 49 |
| -- | no. 19 |
| -- | p. 5671-86 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://doi.org/10.1021/jm0605482">https://doi.org/10.1021/jm0605482</a> |
| Public note | Available from publisher's website |
No items available.