The development of novel 1,2-dihydro-pyrimido[4,5-c]pyridazine based inhibitors of lymphocyte specific kinase (Lck). (Record no. 16353337)

MARC details
000 -LEADER
fixed length control field 01737 a2200493 4500
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20250515030954.0
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 200610s 0 0 eng d
022 ## - INTERNATIONAL STANDARD SERIAL NUMBER
International Standard Serial Number 0960-894X
024 7# - OTHER STANDARD IDENTIFIER
Standard number or code 10.1016/j.bmcl.2006.05.072
Source of number or code doi
040 ## - CATALOGING SOURCE
Original cataloging agency NLM
Language of cataloging eng
Transcribing agency NLM
100 1# - MAIN ENTRY--PERSONAL NAME
Personal name Sabat, Mark
264 #0 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE
Date of production, publication, distribution, manufacture, or copyright notice 20061006
245 00 - TITLE STATEMENT
Title The development of novel 1,2-dihydro-pyrimido[4,5-c]pyridazine based inhibitors of lymphocyte specific kinase (Lck).
Medium [electronic resource]
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Name of publisher, distributor, etc. Bioorganic & medicinal chemistry letters
Date of publication, distribution, etc. Aug 2006
300 ## - PHYSICAL DESCRIPTION
Extent 4257-61 p.
Other physical details digital
500 ## - GENERAL NOTE
General note Publication Type: Journal Article
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Drug Design
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Drug Industry
General subdivision methods
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Enzyme Inhibitors
General subdivision chemistry
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Humans
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Inhibitory Concentration 50
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Lymphocyte Specific Protein Tyrosine Kinase p56(lck)
General subdivision antagonists & inhibitors
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Lymphocytes
General subdivision metabolism
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Models, Chemical
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Models, Molecular
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Pyridazines
General subdivision chemistry
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Pyrimidines
General subdivision chemistry
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Ribonucleosides
General subdivision chemistry
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Structure-Activity Relationship
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Vanrens, John C
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Brugel, Todd A
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Maier, Jennifer
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Laufersweiler, Matthew J
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Golebiowski, Adam
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name De, Biswanath
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Easwaran, Vijayasurian
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Hsieh, Lily C
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Rosegen, Jeff
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Berberich, Steve
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Suchanek, Eric
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Janusz, Michael J
773 0# - HOST ITEM ENTRY
Title Bioorganic & medicinal chemistry letters
Related parts vol. 16
-- no. 16
-- p. 4257-61
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://doi.org/10.1016/j.bmcl.2006.05.072">https://doi.org/10.1016/j.bmcl.2006.05.072</a>
Public note Available from publisher's website

No items available.