Nicotinamide protects human beta cells against chemically-induced necrosis, but not against cytokine-induced apoptosis.
Hoorens, A
Nicotinamide protects human beta cells against chemically-induced necrosis, but not against cytokine-induced apoptosis. [electronic resource] - Diabetologia Jan 1999 - 55-9 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0012-186X
10.1007/s001250051113 doi
Animals
Apoptosis--drug effects
Cell Survival--drug effects
Cells, Cultured
Cytokines--pharmacology
Humans
Hydrogen Peroxide--pharmacology
Interferon-gamma--pharmacology
Interleukin-1--pharmacology
Islets of Langerhans--cytology
Male
Necrosis
Niacinamide--pharmacology
Rats
Rats, Wistar
Recombinant Proteins--pharmacology
Streptozocin--toxicity
Tumor Necrosis Factor-alpha--pharmacology
Nicotinamide protects human beta cells against chemically-induced necrosis, but not against cytokine-induced apoptosis. [electronic resource] - Diabetologia Jan 1999 - 55-9 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0012-186X
10.1007/s001250051113 doi
Animals
Apoptosis--drug effects
Cell Survival--drug effects
Cells, Cultured
Cytokines--pharmacology
Humans
Hydrogen Peroxide--pharmacology
Interferon-gamma--pharmacology
Interleukin-1--pharmacology
Islets of Langerhans--cytology
Male
Necrosis
Niacinamide--pharmacology
Rats
Rats, Wistar
Recombinant Proteins--pharmacology
Streptozocin--toxicity
Tumor Necrosis Factor-alpha--pharmacology