A photodynamic pathway to apoptosis and necrosis induced by dimethyl tetrahydroxyhelianthrone and hypericin in leukaemic cells: possible relevance to photodynamic therapy.

Lavie, G

A photodynamic pathway to apoptosis and necrosis induced by dimethyl tetrahydroxyhelianthrone and hypericin in leukaemic cells: possible relevance to photodynamic therapy. [electronic resource] - British journal of cancer Feb 1999 - 423-32 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

0007-0920

10.1038/sj.bjc.6690066 doi


Anthracenes
Apoptosis--drug effects
Cell Nucleus--drug effects
DNA, Neoplasm--genetics
Dose-Response Relationship, Drug
Gene Expression Regulation, Neoplastic--drug effects
Genes, bcl-1--drug effects
Genes, bcl-2--drug effects
HL-60 Cells--drug effects
Humans
Necrosis
Perylene--analogs & derivatives
Photochemotherapy--methods
Photosensitizing Agents--pharmacology
Proto-Oncogene Proteins--genetics
Proto-Oncogene Proteins c-bcl-2
Radiation-Sensitizing Agents--pharmacology
bcl-2-Associated X Protein