A series of function blocking antibodies against the alpha v beta 3 integrin bind allosteric to the ligand binding site and induce ligand dissociation.

Lin, E C

A series of function blocking antibodies against the alpha v beta 3 integrin bind allosteric to the ligand binding site and induce ligand dissociation. [electronic resource] - Cell adhesion and communication 1998 - 451-64 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

1061-5385

10.3109/15419069809010794 doi


Allosteric Site
Animals
Antibodies, Monoclonal--immunology
Cell Adhesion
Cell Line
Cricetinae
Epitopes, B-Lymphocyte--immunology
Humans
Ligands
Oligopeptides--immunology
Receptors, Immunologic--immunology
Receptors, Vitronectin--immunology
Tumor Cells, Cultured