Simultaneous protection of G156A methylguanine DNA methyltransferase gene-transduced hematopoietic progenitors and sensitization of tumor cells using O6-benzylguanine and temozolomide.

Reese, J S

Simultaneous protection of G156A methylguanine DNA methyltransferase gene-transduced hematopoietic progenitors and sensitization of tumor cells using O6-benzylguanine and temozolomide. [electronic resource] - Clinical cancer research : an official journal of the American Association for Cancer Research Jan 1999 - 163-9 p. digital

Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.

1078-0432


Animals
Antineoplastic Agents--pharmacology
Antineoplastic Agents, Alkylating--pharmacology
Carmustine--pharmacology
Colonic Neoplasms--drug therapy
Dacarbazine--analogs & derivatives
Drug Combinations
Drug Resistance, Neoplasm
Guanine--analogs & derivatives
Hematopoietic Stem Cells--drug effects
Humans
Male
Mice
Mice, Inbred C3H
O(6)-Methylguanine-DNA Methyltransferase--genetics
Temozolomide
Transduction, Genetic
Transfection
Tumor Cells, Cultured