Macrolide biosynthesis: a single cytochrome P450, PicK, is responsible for the hydroxylations that generate methymycin, neomethymycin, and picromycin in Streptomyces venezuelae.

Graziani, E I

Macrolide biosynthesis: a single cytochrome P450, PicK, is responsible for the hydroxylations that generate methymycin, neomethymycin, and picromycin in Streptomyces venezuelae. [electronic resource] - Bioorganic & medicinal chemistry letters Nov 1998 - 3117-20 p. digital

Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.

0960-894X

10.1016/s0960-894x(98)00553-8 doi


Anti-Bacterial Agents--biosynthesis
Bacterial Proteins
Cytochrome P-450 Enzyme System--genetics
Hydroxylation
Macrolides
Mixed Function Oxygenases--genetics
Streptomyces--metabolism