The antihypertensive profile of the angiotensin AT1 receptor antagonist, GR138950, and the influence of potential homeostatic compensatory mechanisms in renal hypertensive rats.

Anderson, I K

The antihypertensive profile of the angiotensin AT1 receptor antagonist, GR138950, and the influence of potential homeostatic compensatory mechanisms in renal hypertensive rats. [electronic resource] - British journal of pharmacology Nov 1998 - 1236-46 p. digital

Publication Type: Journal Article

0007-1188

10.1038/sj.bjp.0702187 doi


Angiotensin Receptor Antagonists
Animals
Anti-Arrhythmia Agents--pharmacology
Antidiuretic Hormone Receptor Antagonists
Antihypertensive Agents--pharmacology
Arginine Vasopressin--analogs & derivatives
Atropine--pharmacology
Benzofurans--pharmacology
Blood Pressure--drug effects
Heart Rate--drug effects
Homeostasis--drug effects
Hormone Antagonists--pharmacology
Hypertension, Renal--drug therapy
Kidney--innervation
Male
Rats
Receptor, Angiotensin, Type 1
Receptor, Angiotensin, Type 2
Splanchnic Nerves--drug effects
Sympathetic Nervous System--drug effects