Catalytic triad of microsomal epoxide hydrolase: replacement of Glu404 with Asp leads to a strongly increased turnover rate.

Arand, M

Catalytic triad of microsomal epoxide hydrolase: replacement of Glu404 with Asp leads to a strongly increased turnover rate. [electronic resource] - The Biochemical journal Jan 1999 - 37-43 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0264-6021


Amino Acid Sequence
Amino Acid Substitution
Animals
Aspartic Acid--metabolism
Base Sequence
Catalytic Domain
DNA Primers
Epoxide Hydrolases--chemistry
Glutamic Acid--metabolism
Kinetics
Microsomes, Liver--enzymology
Molecular Sequence Data
Rats
Recombinant Proteins--chemistry
Sequence Homology, Amino Acid